Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo 153-8902, Japan.
Graduate School of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan.
Nutrients. 2022 May 2;14(9):1907. doi: 10.3390/nu14091907.
Iron deficiency anemia (IDA) and iron deficiency (ID) are frequently observed among endurance athletes. The iron regulatory hormone hepcidin may be involved in IDA and/or ID. Endurance athletes incorporate multiple training sessions, but the influence of repeated bouts of endurance exercise within the same day on iron metabolism remains unclear. Therefore, the purpose of the present study was to investigate the influence of twice a day endurance exercise on iron metabolism, including the hepcidin level, in female long-distance runners. Thirteen female long-distance runners participated in this study. They completed the twice-a-day endurance exercise in the morning and afternoon. Blood samples were collected four times in total: at 06:00 (P0), 14:00 (P8), 20:00 (P14), and 06:00 the next day (P24). In addition to the blood variables, nutritional intake was assessed throughout the exercise day. Serum hepcidin levels were significantly elevated (compared to P0) until the following morning (P24). Moreover, dietary analysis revealed that subjects consumed a low volume of carbohydrates (<6 g/kg body mass/day). In conclusion, twice a day endurance exercise resulted in significant elevation of serum hepcidin level 24 h after completion of the exercise in female long-distance runners. Therefore, athletes with a high risk of anemia should pay attention to training frequency and nutritional intake in order to maintain optimal iron metabolism.
缺铁性贫血（IDA）和缺铁（ID）在耐力运动员中很常见。铁调节激素铁调素可能与 IDA 和/或 ID 有关。耐力运动员会进行多次训练，但同一天内多次耐力运动对铁代谢的影响尚不清楚。因此，本研究的目的是探讨每天两次耐力运动对铁代谢的影响，包括铁调素水平，研究对象为女性长跑运动员。13 名女性长跑运动员参加了这项研究。她们在上午和下午完成了两次耐力运动。总共采集了 4 次血样：06:00（P0）、14:00（P8）、20:00（P14）和第二天 06:00（P24）。除了血液变量外，还在整个运动日评估了营养摄入。血清铁调素水平显著升高（与 P0 相比），直到第二天早上（P24）。此外，膳食分析显示，受试者的碳水化合物摄入量较低（<6 g/kg 体重/天）。总之，女性长跑运动员在完成两次耐力运动后 24 小时，血清铁调素水平显著升高。因此，有发生贫血风险的运动员应注意训练频率和营养摄入，以保持最佳铁代谢。
