Namiki M, Nakamura M, Okuyama A, Sonoda T, Nishimune Y, Takatsuka D, Matsumoto K
Fertil Steril. 1987 Mar;47(3):475-80. doi: 10.1016/s0015-0282(16)59058-x.
The influence of temperature on Leydig and Sertoli cell functions was investigated in two experiments. One experiment was performed with testes of men with or without varicocele, because the temperature differs between right and left testes of men with left varicocele and right testes of men without varicocele. There were no significant differences in follicle-stimulating hormone (FSH), human chorionic gonadotropin (hCG) receptors, and testosterone (T) concentrations among the testes. The other experiment was performed with the use of testicular organ culture. Specific binding sites for FSH, hCG, and T production were similar in cultured testes maintained at 33 degrees and 37 degrees C for 7 days. It is concluded that high temperature may not disturb Leydig and Sertoli cell functions in the short term.
在两项实验中研究了温度对睾丸间质细胞和支持细胞功能的影响。一项实验是对患有或未患有精索静脉曲张的男性睾丸进行的,因为左侧精索静脉曲张男性的左右睾丸之间以及未患精索静脉曲张男性的右侧睾丸与左侧睾丸之间温度存在差异。这些睾丸之间的促卵泡激素(FSH)、人绒毛膜促性腺激素(hCG)受体和睾酮(T)浓度没有显著差异。另一项实验是使用睾丸器官培养进行的。在33摄氏度和37摄氏度下维持7天的培养睾丸中,FSH、hCG的特异性结合位点以及T的产生情况相似。得出的结论是,高温在短期内可能不会干扰睾丸间质细胞和支持细胞的功能。