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温度对人类睾丸支持细胞和间质细胞功能的影响。

Influence of temperature on the function of Sertoli and Leydig cells of human testes.

作者信息

Namiki M, Nakamura M, Okuyama A, Sonoda T, Nishimune Y, Takatsuka D, Matsumoto K

出版信息

Fertil Steril. 1987 Mar;47(3):475-80. doi: 10.1016/s0015-0282(16)59058-x.

DOI:10.1016/s0015-0282(16)59058-x
PMID:3556625
Abstract

The influence of temperature on Leydig and Sertoli cell functions was investigated in two experiments. One experiment was performed with testes of men with or without varicocele, because the temperature differs between right and left testes of men with left varicocele and right testes of men without varicocele. There were no significant differences in follicle-stimulating hormone (FSH), human chorionic gonadotropin (hCG) receptors, and testosterone (T) concentrations among the testes. The other experiment was performed with the use of testicular organ culture. Specific binding sites for FSH, hCG, and T production were similar in cultured testes maintained at 33 degrees and 37 degrees C for 7 days. It is concluded that high temperature may not disturb Leydig and Sertoli cell functions in the short term.

摘要

在两项实验中研究了温度对睾丸间质细胞和支持细胞功能的影响。一项实验是对患有或未患有精索静脉曲张的男性睾丸进行的,因为左侧精索静脉曲张男性的左右睾丸之间以及未患精索静脉曲张男性的右侧睾丸与左侧睾丸之间温度存在差异。这些睾丸之间的促卵泡激素(FSH)、人绒毛膜促性腺激素(hCG)受体和睾酮(T)浓度没有显著差异。另一项实验是使用睾丸器官培养进行的。在33摄氏度和37摄氏度下维持7天的培养睾丸中,FSH、hCG的特异性结合位点以及T的产生情况相似。得出的结论是,高温在短期内可能不会干扰睾丸间质细胞和支持细胞的功能。

相似文献

1
Influence of temperature on the function of Sertoli and Leydig cells of human testes.温度对人类睾丸支持细胞和间质细胞功能的影响。
Fertil Steril. 1987 Mar;47(3):475-80. doi: 10.1016/s0015-0282(16)59058-x.
2
[Influence of temperature on the function of the human testes].[温度对人体睾丸功能的影响]
Hinyokika Kiyo. 1988 Oct;34(10):1767-70.
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Testicular gonadotropin receptors in men with hypogonadotropic hypogonadism.低促性腺激素性性腺功能减退男性的睾丸促性腺激素受体
Arch Androl. 1988;20(1):81-5. doi: 10.3109/01485018808987056.
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Changes in testicular function induced by short-term exposure of the rat testis to heat: further evidence for interaction of germ cells, Sertoli cells and Leydig cells.大鼠睾丸短期受热诱导的睾丸功能变化:生殖细胞、支持细胞和间质细胞相互作用的进一步证据
Int J Androl. 1984 Jun;7(3):244-57. doi: 10.1111/j.1365-2605.1984.tb00781.x.
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Testicular FSH and hCG receptors in Sertoli-cell-only syndrome.
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[Endocrinological profile of human spermatogenic impairment--evaluation of function of Leydig and Sertoli cells in vivo or in vitro studies].[人类生精功能障碍的内分泌特征——睾丸间质细胞和支持细胞功能的体内或体外研究评估]
Hinyokika Kiyo. 1988 Nov;34(11):1943-8.
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[Effect of experimental left varicocele on rat Leydig cell function].[实验性左侧精索静脉曲张对大鼠睾丸间质细胞功能的影响]
Nihon Hinyokika Gakkai Zasshi. 1995 Feb;86(2):308-15. doi: 10.5980/jpnjurol1989.86.308.
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Cultured Sertoli cell-mediated FSH stimulatory effect on Leydig cell steroidogenesis.培养的支持细胞介导的促卵泡激素对睾丸间质细胞类固醇生成的刺激作用。
Am J Physiol. 1985 Feb;248(2 Pt 1):E176-81. doi: 10.1152/ajpendo.1985.248.2.E176.
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FSH regulates cultured Leydig cell function via Sertoli cell proteins: an in vitro study.卵泡刺激素通过支持细胞蛋白调节培养的睾丸间质细胞功能:一项体外研究。
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An activated human follicle-stimulating hormone (FSH) receptor stimulates FSH-like activity in gonadotropin-deficient transgenic mice.活化的人促卵泡激素(FSH)受体可刺激促性腺激素缺乏的转基因小鼠产生类似FSH的活性。
Mol Endocrinol. 2002 Nov;16(11):2582-91. doi: 10.1210/me.2002-0032.

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