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参与者导向的干预措施定制与改善南亚 2 型糖尿病成年患者的血糖控制有关。

Participant-Directed Intervention Tailoring Is Associated With Improvements in Glycemic Control for South Asian Adults With Type 2 Diabetes.

机构信息

Division of Endocrinology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

Can J Diabetes. 2022 Apr;46(3):287-293. doi: 10.1016/j.jcjd.2021.11.003. Epub 2021 Nov 27.

DOI:10.1016/j.jcjd.2021.11.003
PMID:35568430
Abstract

OBJECTIVES

Our aim was to determine the impact of a 3-month diabetes self-management education and support (DSME/DSMS) intervention involving both professional and peer support on glycemic control and diabetes distress in South Asian adults with type 2 diabetes (T2D) living in Metro Vancouver.

METHODS

We recruited 114 South Asian adults with T2D for a study conducted across 7 sites in Metro Vancouver. A previous DSME/DSMS intervention was modified using participant feedback. Participants attended the updated intervention involving 6 biweekly group-based DSME sessions co-led by a diabetes educator and peer leader and 6 biweekly DSMS sessions delivered by a peer leader. Assessments were conducted at baseline and 3 months. Primary outcomes were glycated hemoglobin (A1C) and diabetes distress. Secondary outcomes included apolipoprotein B, blood pressure (BP), height and weight, waist circumference, diabetes support and depressive symptoms.

RESULTS

After the 3-month intervention, linear mixed-effects modelling demonstrated A1C decreased significantly from 8.2% (66 mmol/mol) to 7.8% (62 mmol/mol) (p<0.0001), as did body mass index (from 30.02 to 29.7 kg/m; p=0.0005) and diastolic BP (from 75.86 to 70.78 mmHg; p<0.0001). These reductions persisted after adjusting for the fixed-effects of age, sex, intensification of diabetes and BP medication, as well as random effects for subject and location.

CONCLUSIONS

Participation in a professional plus peer-led intervention tailored by South Asian adults with T2D is associated with improved glycemic control and other favourable health outcomes.

摘要

目的

我们旨在确定为期 3 个月的糖尿病自我管理教育和支持(DSME/DSMS)干预措施对生活在温哥华大都市区的南亚 2 型糖尿病(T2D)成年人的血糖控制和糖尿病困扰的影响,该干预措施涉及专业人员和同伴支持。

方法

我们招募了 114 名南亚 T2D 成年人,在温哥华大都市区的 7 个地点进行了一项研究。先前的 DSME/DSMS 干预措施根据参与者的反馈进行了修改。参与者参加了经过更新的干预措施,该措施包括 6 次双周小组 DSME 课程,由糖尿病教育者和同伴领袖共同领导,以及 6 次双周 DSMS 课程,由同伴领袖提供。在基线和 3 个月时进行评估。主要结果是糖化血红蛋白(A1C)和糖尿病困扰。次要结果包括载脂蛋白 B、血压(BP)、身高和体重、腰围、糖尿病支持和抑郁症状。

结果

经过 3 个月的干预,线性混合效应模型显示 A1C 从 8.2%(66mmol/mol)显著下降至 7.8%(62mmol/mol)(p<0.0001),体重指数(从 30.02 降至 29.7kg/m;p=0.0005)和舒张压(从 75.86 降至 70.78mmHg;p<0.0001)也下降。在调整年龄、性别、糖尿病强化和 BP 药物的固定效应以及受试者和地点的随机效应后,这些结果仍然存在。

结论

参与由南亚 T2D 成年人量身定制的专业加同伴领导的干预措施与改善血糖控制和其他有利的健康结果相关。

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