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肠淋巴管扩张症中的低镁血症:病例报告及文献复习。

Hypomagnesemia in intestinal lymphangiectasia: a case report and review of the literature.

机构信息

Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, China.

Department of Gastroenterology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Shuaifuyuan, Dongcheng District, Beijing, 100730, China.

出版信息

BMC Gastroenterol. 2022 May 15;22(1):246. doi: 10.1186/s12876-022-02318-6.

Abstract

BACKGROUND

Intestinal lymphangiectasia (IL) is a rare disease characterized by dilation of lymphatic vessels and leakage of lymphatic fluids into the intestinal lumen, causing depletion of lymphocytes, protein, lipids, fat-soluble vitamins, and electrolytes. Hypomagnesemia can occur in IL patients but is seldom discussed.

CASE PRESENTATION

A 30-year-old Tibetan woman who had chronic diarrhea, edema, tetany, and tingling was diagnosed with IL. Prominent hypomagnesemia was noticed. She was treated with a medium-chain triglyceride (MCT) diet and nutrient supplementation with satisfactory results. We also present a systematic review of hypomagnesemia in IL cases from the published literature.

CONCLUSIONS

Hypomagnesemia may be an overlooked complication of IL, thus monitoring serum magnesium concentrations in IL patients is crucial.

摘要

背景

肠淋巴管扩张症(IL)是一种罕见的疾病,其特征是淋巴管扩张和淋巴液渗漏到肠腔中,导致淋巴细胞、蛋白质、脂质、脂溶性维生素和电解质流失。低镁血症可发生在 IL 患者中,但很少被讨论。

病例介绍

一位 30 岁的藏族女性,患有慢性腹泻、水肿、抽搐和刺痛,被诊断为 IL。明显的低镁血症。她接受了中链甘油三酯(MCT)饮食和营养补充治疗,效果满意。我们还对已发表文献中 IL 病例的低镁血症进行了系统回顾。

结论

低镁血症可能是 IL 的一个被忽视的并发症,因此监测 IL 患者的血清镁浓度至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0375/9107688/a70b5f22ffe3/12876_2022_2318_Fig1_HTML.jpg

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