Bhagat Devidas S, Gurnule Wasudeo B, Bumbrah Gurvinder S, Koinkar Pankaj, Chawla Pooja A
Department of Forensic Chemistry and Toxicology, Government Institute of Forensic Science, Aurangabad, 431 004, (MS), India.
Department of Chemistry, Kamla Nehru Mahavidyalaya, Nagpur, 440024, (MS), India.
Curr Pharm Biotechnol. 2023;24(1):86-100. doi: 10.2174/1389201023666220513101628.
The synthesis of biogenic nanoparticles from readily available natural resources may have large demand in numerous fields including pharmaceuticals and medicine. The biogenic nanoparticles catch the attention of the scientific community due to their low cytotoxicity and biocompatibility. Chemical, physical, and greener methods are used for the synthesis of biogenic nanoparticles. Researchers used eco-friendly and nontoxic approaches in the synthesis of this nanoparticle. This nanomaterial-based medicine plays a vital role in the management of public health, including earlier detection of disease, therapeutics candidates in the treatment of cancer. Biogenic nanocomposites are environmentally benign candidates that include fabrication of various composites, detoxification, and act as a catalyst in the biodegradation process. In this review article, we emphasize the recently reported methods used for synthesis, summarizing their biomedical applications and commercial and environmentally benign applications. Synthetic strategies include greener, chemical, physical, and biogenic methods and their role in surface modifiers involves various biomedical, commercial, and environmental-related applications. Moreover, we glimpse existing status, key contests, and future perspectives.
利用现成的自然资源合成生物源纳米颗粒在包括制药和医学在内的众多领域可能有巨大需求。生物源纳米颗粒因其低细胞毒性和生物相容性而引起科学界的关注。化学、物理和更环保的方法被用于合成生物源纳米颗粒。研究人员在这种纳米颗粒的合成中采用了生态友好且无毒的方法。这种基于纳米材料的药物在公共卫生管理中发挥着至关重要的作用，包括疾病的早期检测、癌症治疗中的候选治疗方法。生物源纳米复合材料是环境友好型材料，包括各种复合材料的制造、解毒以及在生物降解过程中充当催化剂。在这篇综述文章中，我们强调了最近报道的合成方法，总结了它们的生物医学应用以及商业和环境友好型应用。合成策略包括更环保、化学、物理和生物源方法，它们在表面改性剂中的作用涉及各种生物医学、商业和与环境相关的应用。此外，我们还展望了现有状况、关键挑战和未来前景。
