Silverberg Orli M, Cyrenne Benoit M, Croitoru David, Sandre Matthew K, Pon Kucy
Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
SAGE Open Med Case Rep. 2022 May 11;10:2050313X221093444. doi: 10.1177/2050313X221093444. eCollection 2022.
Liquid silicone is a relatively inexpensive injectable used for soft tissue augmentation. Injection of silicone is associated with a risk of delayed granuloma formation associated with elevated levels of tumour necrosis factor-α. We report a case of recalcitrant silicone granulomas following facial injections of silicone successfully treated with tumour necrosis factor-α blockade. Our case, as well as previous reports, demonstrates the effectiveness of this therapy for the treatment of foreign body granulomas from due to silicone.
液态硅胶是一种相对便宜的可注射材料，用于软组织填充。注射硅胶存在与肿瘤坏死因子-α水平升高相关的迟发性肉芽肿形成风险。我们报告了一例面部注射硅胶后顽固性硅胶肉芽肿病例，该病例通过肿瘤坏死因子-α阻断成功治愈。我们的病例以及先前的报告均证明了这种疗法对治疗由硅胶引起的异物肉芽肿的有效性。
