Zhang Qian, Yang Lihua, Yang Fengjuan, Liu Lian, Jiang Xian
Department of Dermatology, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Clin Cosmet Investig Dermatol. 2023 Apr 3;16:861-867. doi: 10.2147/CCID.S403601. eCollection 2023.
Mesotherapy is a popular treatment that delivers substances deep into the skin but induces foreign body-type granulomatous reactions. However, such reactions caused by unauthorized use of topical tranexamic acid products in mesotherapy have never been reported before. We herein demonstrated a case of a 33-year-old woman with multiple mesotherapy-induced foreign body-type granulomas disseminated across her face. The patient was diagnosed with echo-color Doppler (ECD) and successfully treated with medications including minocycline hydrochloride. Then, we reviewed the differential diagnosis and current treatment for foreign body-type granulomatous reaction.
中胚层疗法是一种将物质输送到皮肤深层但会引发异物型肉芽肿反应的流行治疗方法。然而，此前从未有过关于在中胚层疗法中未经授权使用外用氨甲环酸产品导致此类反应的报道。我们在此展示了一例33岁女性的病例，她面部出现了多处因中胚层疗法引起的异物型肉芽肿。该患者通过超声彩色多普勒（ECD）进行了诊断，并成功接受了包括盐酸米诺环素在内的药物治疗。然后，我们回顾了异物型肉芽肿反应的鉴别诊断和当前治疗方法。
