高通量功能表观基因组学的发展：使用测序筛选的 CRISPR 单细胞转座酶可及染色质测定法。
Developments in high-throughput functional epigenomics: CRISPR-single-cell assay for transposase-accessible chromatin using sequencing screens.
机构信息
Weill Cornell Medical College, Department of Neurological Surgery, New York, NY 10021, USA.
出版信息
Epigenomics. 2022 Jun;14(11):645-649. doi: 10.2217/epi-2022-0093. Epub 2022 May 16.
PMID:35574596
Abstract
Tweetable abstract CRISPR-scATAC-seq screens pave the way for high-throughput functional epigenomics by linking perturbations to a broad view of epigenetic state and messages hidden within accessible sequences.
摘要
可推文的摘要
CRISPR-scATAC-seq 筛选为高通量功能表观基因组学铺平了道路，它将扰动与广泛的表观状态视图以及可访问序列中隐藏的信息联系起来。
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