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多发性硬化症的运动诱发电位,多年随访数据集。

Motor evoked potentials for multiple sclerosis, a multiyear follow-up dataset.

机构信息

Biomedical Research Institute (BIOMED), Hasselt University, 3500, Hasselt, Belgium.

Data Science Institute (DSI), Hasselt University, 3500, Hasselt, Belgium.

出版信息

Sci Data. 2022 May 16;9(1):207. doi: 10.1038/s41597-022-01335-0.

Abstract

Multiple sclerosis (MS) is a chronic disease affecting millions of people worldwide. Through the demyelinating and axonal pathology of MS, the signal conduction in the central nervous system is affected. Evoked potential measurements allow clinicians to monitor this process and can be used for decision support. We share a dataset that contains motor evoked potential (MEP) measurements, in which the brain is stimulated and the resulting signal is measured in the hands and feet. This results in time series of 100 milliseconds long. Typically, both hands and feet are measured in one hospital visit. The dataset contains 5586 visits of 963 patients, performed in day-to-day clinical care over a period of 6 years. The dataset consists of approximately 100,000 MEP. Clinical metadata such as the expanded disability status scale, sex, and age is also available. This dataset can be used to explore the role of evoked potentials in MS research and patient care. It may also be used as a benchmark for time series analysis and predictive modelling.

摘要

多发性硬化症(MS)是一种影响全球数百万人的慢性疾病。通过 MS 的脱髓鞘和轴突病理学,中枢神经系统的信号传导受到影响。诱发电位测量可让临床医生监测这一过程,并可用于决策支持。我们分享了一个数据集,其中包含运动诱发电位(MEP)测量值,在此过程中,大脑会受到刺激,手部和脚部会测量得到的信号。这会产生 100 毫秒长的时间序列。通常,一次医院就诊会同时测量双手和双脚。该数据集包含 963 名患者的 5586 次就诊,这些就诊是在日常临床护理中在 6 年期间进行的。该数据集包含大约 10 万次 MEP。还可以获得扩展残疾状况量表、性别和年龄等临床元数据。该数据集可用于探索诱发电位在 MS 研究和患者护理中的作用。它也可以用作时间序列分析和预测建模的基准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc24/9110383/3ef74f2e281e/41597_2022_1335_Fig1_HTML.jpg

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