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基于潜在类别分析方法研究中国人群体力活动类型与心血管疾病的相关性。

Study on the associations of physical activity types and cardiovascular diseases among Chinese population using latent class analysis method.

机构信息

School of Public Health, Southeast University, 87 Dingjiaqiao Road, Nanjing, 210009, Jiangsu Province, China.

Department of Chronic Non-Communicable Disease Control, Jiangsu Provincial Center for Disease Control and Prevention, 172 Jiangsu Road, Nanjing, 210009, Jiangsu Province, China.

出版信息

Sci Rep. 2022 May 16;12(1):8081. doi: 10.1038/s41598-022-12182-9.

Abstract

Previous studies reported on the association between physical activity (PA) and cardiovascular diseases (CVD) among the Western population. However, evidence on the association between different patterns of PA and the risk of CVD among Chinese population are limited. This study aims to evaluate the association of different PA types and the risk of CVD in a Chinese adult population. A total of 3568 community residents were recruited from Jiangsu Province of China using a stratified multistage cluster sampling method. The latent class analysis method was employed to identify the types of PA, and the Framingham risk score (FRS) was used to estimate the risk of CVD within 10 years. Three types of PA were identified: CLASS1 represented participants with high occupational PA and low sedentary PA (32.1% of male, 26.5% of female), ClASS2 represented those engaging in low occupational PA and high leisure-time PA (27.0% of male, 14.2% of female), and CLASS3 represented low leisure-time and high sedentary PA (40.9% of male, 59.3% of female). The average of FRS in males was higher than that in females across PA types. CLASS1 (OR = 0.694, 95%CI 0.553-0.869) and CLASS2 (OR = 0.748, 95%CI 0.573-0.976) were both found to be protective against CVD in males; however, such associations were not statistically significant among females. Therefore, higher occupational or leisure-time PA appear to be associated with decreased risk of CVD, while more sedentary behaviors may increase the risk of CVD, particularly for male Chinese adults.

摘要

先前的研究报告了西方人群中体力活动(PA)与心血管疾病(CVD)之间的关联。然而,关于中国人群中不同类型 PA 与 CVD 风险之间的关联证据有限。本研究旨在评估中国成年人群中不同类型 PA 与 CVD 风险之间的关联。采用分层多阶段聚类抽样方法,从中国江苏省招募了 3568 名社区居民。采用潜在类别分析方法识别 PA 类型,采用 Framingham 风险评分(FRS)估计 10 年内 CVD 的风险。确定了三种类型的 PA:CLASS1 代表高职业 PA 和低久坐 PA 的参与者(男性占 32.1%,女性占 26.5%),ClASS2 代表从事低职业 PA 和高休闲时间 PA 的参与者(男性占 27.0%,女性占 14.2%),CLASS3 代表低休闲时间和高久坐 PA 的参与者(男性占 40.9%,女性占 59.3%)。男性的 FRS 平均值在不同 PA 类型中均高于女性。CLASS1(OR=0.694,95%CI 0.553-0.869)和 CLASS2(OR=0.748,95%CI 0.573-0.976)在男性中均被发现对 CVD 具有保护作用;然而,在女性中,这种关联并不具有统计学意义。因此,较高的职业或休闲时间 PA 似乎与降低 CVD 风险相关,而更多的久坐行为可能会增加 CVD 风险,尤其是对于中国成年男性。

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