Department of Medicine (DIMED), Geriatrics Division, University of Padua, Italy.
Department of Medicine (DIMED), Geriatrics Division, University of Padua, Italy.
Nutrition. 2022 Jul-Aug;99-100:111653. doi: 10.1016/j.nut.2022.111653. Epub 2022 Mar 11.
Aging is associated with low-grade chronic inflammation contributing to a decline in lung performance. The Dietary Inflammatory Index (DII) has been introduced to evaluate the inflammatory potential of different diets, which may further affect individuals' respiratory function. This study investigates the association between DII and lung performance in older adults.
This cross-sectional study included 155 adults aged ≥65 y recruited at public gyms in Padua, Italy. Participants were assessed on medical history, biochemical parameters, body composition (through dual energy x-ray absorptiometry), anthropometry, and lung function (by spirometry). Based on individuals' dietary habits, we computed their DII and categorized participants in the lower DII (comprising those in the lowest DII tertile) or the higher DII (comprising those in the highest DII tertiles) groups. The association of DII with forced expiratory volume in the first second (FEV1) and forced vital capacity (FVC) was tested through multivariable linear regression analyses in the total sample and stratified by body mass index (<25 kg/m versus ≥25 kg/m).
The mean age of the sample was 71.2 y and 80% were women. Individuals in the higher DII group had FEV1 and FVC values reduced by 0.15 L (95% CI, -0.29 to -0.01 L) and 0.25 L (95% CI, -0.43 to -0.07 L), respectively, as compared with those in the lower DII group. Results seemed to be more marked among participants with excess weight conditions.
Pro-inflammatory diets may affect lung function in fit older people, and this effect may be exacerbated in overweight or obese individuals.
衰老与低度慢性炎症有关，后者导致肺功能下降。膳食炎症指数（DII）已被引入以评估不同饮食的炎症潜力，这可能进一步影响个体的呼吸功能。本研究调查了 DII 与老年人肺功能之间的关系。
这是一项横断面研究，包括意大利帕多瓦市公共健身房招募的 155 名年龄≥65 岁的成年人。参与者接受了病史、生化参数、身体成分（通过双能 X 射线吸收法）、人体测量学和肺功能（通过肺活量测定法）评估。根据个体的饮食习惯，我们计算了他们的 DII，并将参与者分为低 DII 组（包括 DII 最低三分位组）或高 DII 组（包括 DII 最高三分位组）。通过多元线性回归分析，在总样本中和按体重指数（<25 kg/m2 与≥25 kg/m2）分层，检验了 DII 与第一秒用力呼气量（FEV1）和用力肺活量（FVC）之间的关系。
样本的平均年龄为 71.2 岁，80%为女性。与低 DII 组相比，高 DII 组的 FEV1 和 FVC 值分别降低了 0.15 L（95%CI，-0.29 至-0.01 L）和 0.25 L（95%CI，-0.43 至-0.07 L）。结果在超重或肥胖人群中似乎更为明显。
促炎饮食可能会影响健康老年人的肺功能，而这种影响在超重或肥胖个体中可能会加剧。
