埃塞俄比亚西北部贡德尔地区住院医师对抗菌药物使用及耐药性的知识、态度和实践
Knowledge, attitude and practices of residents toward antimicrobial usage and resistance in Gondar, Northwest Ethiopia.
作者信息
Dejene Haileyesus, Birhanu Rediet, Tarekegn Zewdu Seyoum
机构信息
Department of Veterinary Epidemiology and Public Health, College of Veterinary Medicine and Animal Sciences, University of Gondar, Gondar, Amhara, Ethiopia.
Department of Veterinary Paraclinical Studies, College of Veterinary Medicine and Animal Sciences, University of Gondar, Gondar, Amhara, Ethiopia.
出版信息
One Health Outlook. 2022 May 18;4(1):10. doi: 10.1186/s42522-022-00066-x.
BACKGROUND
Antimicrobials are essential for human and animal health. Drug resistance to an antimicrobial agent follows the introduction of a new antimicrobial agent. Evidence suggests that the public plays an important role in the risk, increase, and spread of antimicrobial resistance. This study aimed to assess the knowledge, attitudes, and practices of the Gondar City residents regarding antimicrobial use and resistance.
METHODS
A cross-sectional study was conducted from April to July 2021 on 400 randomly selected Gondar city residents using a pretested semi-structured questionnaire. The descriptive and chi-square tests were used to analyse the data.
RESULTS
The response rate was one hundred percent. Approximately 75% of respondents were men, with 32% having completed secondary school. Nearly 74% and 35% of participants were married and worked in various government jobs. Furthermore, 48%, 54%, and 50% of respondents, respectively, had moderate knowledge, a positive attitude, and good practice concerning antimicrobial use and resistance. The chi-square analysis revealed a significant (p < 0.05) disparity between knowledge and educational level, marital status, and position in the house. The respondents' attitude levels were also significantly associated (p < 0.05) with their educational level, marital status, occupation, and position in the house. Respondents' practice levels were also significantly associated (p < 0.05) with their educational level and occupation. The study also found a significant relationship between respondents' knowledge and attitude (χ2 = 215.23, p ≤ 0.01), knowledge and practice (χ2 = 147.2, p ≤ 0.01), and attitude and practice (χ2 = 116.03, p ≤ 0.01).
CONCLUSION
This study found that study participants had some misconceptions about antimicrobial use and resistance. As a result, both enforcing antimicrobial regulation and educating people about antimicrobial use are advised.
背景
抗菌药物对人类和动物健康至关重要。在引入新的抗菌药物后，会出现对该抗菌药物的耐药性。有证据表明，公众在抗菌药物耐药性的风险、增加和传播中起着重要作用。本研究旨在评估贡德尔市居民对抗菌药物使用和耐药性的知识、态度和行为。
方法
2021年4月至7月，采用预先测试的半结构化问卷，对400名随机抽取的贡德尔市居民进行了横断面研究。使用描述性统计和卡方检验分析数据。
结果
回复率为100%。约75%的受访者为男性，32%的受访者完成了中学教育。近74%和35%的参与者已婚并在政府各部门工作。此外，分别有48%、54%和50%的受访者对抗菌药物使用和耐药性有中等知识、积极态度和良好行为。卡方分析显示，知识与教育水平、婚姻状况和家庭地位之间存在显著差异（p<0.05）。受访者的态度水平也与他们的教育水平、婚姻状况、职业和家庭地位显著相关（p<0.05）。受访者的行为水平也与他们的教育水平和职业显著相关（p<0.05）。该研究还发现受访者的知识与态度（χ2=215.23，p≤0.01）、知识与行为（χ2=147.2，p≤0.01）以及态度与行为（χ2=116.03，p≤0.01）之间存在显著关系。
结论
本研究发现，研究参与者对抗菌药物使用和耐药性存在一些误解。因此，建议加强抗菌药物监管并对民众进行抗菌药物使用教育。
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