酵母突变体rna 1会影响核糖体RNA以及信使RNA进入多核糖体的过程。

Yeast mutant, rna 1, affects the entry into polysomes of ribosomal RNA as well as messenger RNA.

作者信息

Petersen N S, Nierlich D P

出版信息

Mol Gen Genet. 1978 Jul 4;162(3):319-22. doi: 10.1007/BF00268857.

Abstract

The entry of newly labeled ribosomal subunits and mRNA into polysomes was examined in the yeast mutant rna1. The entry of both types of RNA into polysomes is inhibited rapidly at the restrictive temperature. Analysis of the labeling of the ATP pool and the kinetics of synthesis and processing of mRNA at the restrictive temperature leads to the conclusion that the primary defect in the mutant affects transport of both ribosomes and messenger across the nuclear membrane.

摘要

在酵母突变体rna1中研究了新标记的核糖体亚基和mRNA进入多核糖体的情况。在限制温度下，这两种类型的RNA进入多核糖体的过程会迅速受到抑制。对限制温度下ATP池的标记以及mRNA合成和加工动力学的分析得出结论，该突变体的主要缺陷影响核糖体和信使RNA穿过核膜的转运。