Ingram Martha-Conley E, Nagalla Monica, Shan Ying, Nasca Brian J, Thomas Arielle C, Reddy Susheel, Bilimoria Karl Y, Stey Anne
Surgical Outcomes Quality Improvement Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Committee on Trauma, American College of Surgeons, Chicago, Illinois.
JAMA Surg. 2022 Jul 1;157(7):609-616. doi: 10.1001/jamasurg.2022.1550.
Differences in time to diagnostic and therapeutic measures can contribute to disparities in outcomes. However, whether there is an association of timeliness by sex for trauma patients is unknown.
To investigate whether sex-based differences in time to definitive interventions exist for trauma patients in the US and whether these differences are associated with outcomes.
DESIGN, SETTING, AND PARTICIPANTS: This was a retrospective cohort study conducted from July 2020 to July 2021, using the 2013 to 2016 Trauma Quality Improvement Program (TQIP) databases from level I to III trauma centers in the US. Patients 18 years or older with an Injury Severity Score (ISS) greater than 15 and who carried diagnoses of traumatic brain injury, intra-abdominal injury, pelvic fracture, femur fracture, and spinal injury as a result of their trauma were included in the study. Data were analyzed from July 2020 to July 2021.
Primary outcomes assessed timeliness to interventions, using Wilcoxon signed rank and χ2 tests. Secondary outcomes included location of discharge after injury, using propensity score-matched generalized estimating equations modeling.
Of the 28 332 patients included, 20 002 (70.6%) were male patients (mean [SD] age, 43.3 [18.2] years) and 8330 (29.4%) were female patients (mean [SD] age, 48.5 [21.1] years), with significantly different distributions of ISS scores (ISS score 16-24: male patient, 10 622 [53.1%]; female patient, 4684 [56.2%]; ISS score 41-74: male patient, 2052 [10.3%]; female patient, 852 [10.2%]). Male patients more frequently had abdominal (4257 [21.3%] vs 1268 [15.2%]) and spinal cord (3989 [20.0%] vs 1274 [15.3%]) injuries, whereas female patients experienced greater proportions of femur (3670 [44.0%] vs 8422 [42.1%]) and pelvic (3970 [47.6%] vs 6963 [34.8%]) fractures. Female patients experienced significantly longer emergency department length of stay (median [IQR], 184 [92-314] minutes vs 172 [86-289] minutes; P < .001), longer time in pretriage (median [IQR], 52 [36-80] minutes vs 49 [34-77] minutes; P < .001), and increased likelihood of discharge to nursing or long-term care facilities instead of home after matching by age, ISS, mechanism, and injury type (male patient:female patient, odds ratio, 0.72; 95% CI, 0.67-0.78).
Results of this cohort study suggest that female trauma patients experienced slightly longer delays in trauma care and had a higher likelihood of discharge to long-term care facilities than their male counterparts.
诊断和治疗措施的时间差异可能导致结果的差异。然而,创伤患者的及时性是否存在性别差异尚不清楚。
调查美国创伤患者在确定性干预时间上是否存在基于性别的差异,以及这些差异是否与结果相关。
设计、设置和参与者:这是一项回顾性队列研究,于2020年7月至2021年7月进行,使用了美国一级至三级创伤中心2013年至2016年的创伤质量改进计划(TQIP)数据库。纳入研究的患者年龄在18岁及以上,损伤严重程度评分(ISS)大于15,且因创伤被诊断为创伤性脑损伤、腹部损伤、骨盆骨折、股骨骨折和脊髓损伤。数据于2020年7月至2021年7月进行分析。
主要结局使用Wilcoxon符号秩检验和χ2检验评估干预的及时性。次要结局包括受伤后出院地点,使用倾向得分匹配的广义估计方程建模。
在纳入的28332例患者中,20002例(70.6%)为男性患者(平均[标准差]年龄,43.3[18.2]岁),8330例(29.4%)为女性患者(平均[标准差]年龄,48.5[21.1]岁),ISS评分分布有显著差异(ISS评分16 - 24:男性患者,10622例[53.1%];女性患者,4684例[56.2%];ISS评分41 - 74:男性患者,2052例[10.3%];女性患者,852例[10.2%])。男性患者腹部损伤(4257例[21.3%]对1268例[15.2%])和脊髓损伤(3989例[20.0%]对1274例[15.3%])更为常见,而女性患者股骨骨折(3670例[44.0%]对8422例[42.1%])和骨盆骨折(3970例[47.6%]对6963例[34.8%])的比例更高。女性患者在急诊科的住院时间明显更长(中位数[四分位间距],184[92 - 314]分钟对172[86 - 289]分钟;P <.001),预检时间更长(中位数[四分位间距],52[36 - 80]分钟对49[34 - 77]分钟;P <.001),并且在按年龄、ISS、机制和损伤类型匹配后,出院到护理机构或长期护理机构而非家中的可能性增加(男性患者:女性患者,比值比,0.72;95%置信区间,0.67 - 0.78)。
这项队列研究的结果表明,女性创伤患者在创伤护理中经历的延迟略长,并且与男性患者相比,出院到长期护理机构的可能性更高。