Division of Nephrology, Nanfang Hospital, Southern Medical University; National Clinical Research Center for Kidney Disease; State Key Laboratory of Organ Failure Research; Guangdong Provincial Institute of Nephrology, Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou Regenerative Medicine and Health Guangdong Laboratory; Guangdong Provincial Clinical Research Center for Kidney Disease, Guangzhou, China; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Institute of Biomedicine, Anhui Medical University, Hefei, China.
Division of Nephrology, Nanfang Hospital, Southern Medical University; National Clinical Research Center for Kidney Disease; State Key Laboratory of Organ Failure Research; Guangdong Provincial Institute of Nephrology, Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou Regenerative Medicine and Health Guangdong Laboratory; Guangdong Provincial Clinical Research Center for Kidney Disease, Guangzhou, China.
Am J Med. 2022 Nov;135(11):1362-1370.e6. doi: 10.1016/j.amjmed.2022.04.023. Epub 2022 May 15.
The relation of domestic physical activity with hypertension remains uncertain. We aimed to evaluate the prospective relation of domestic physical activity and new-onset hypertension among Chinese males and females.
A total of 9254 adults who were free of hypertension at baseline were enrolled from the China Health and Nutrition Survey. Data on domestic physical activity were obtained by using self-reported questionnaires, and calculated as metabolic equivalent task (MET)-hours/week. Metabolic equivalent task-hours/week may account for both intensity and time spent on activities. The study outcome was new-onset hypertension, defined as systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg or diagnosed by physician or under antihypertensive treatment during the follow-up.
A total of 2892 participants developed hypertension during 81996 person-years of follow-up. Overall, there were reversed J-shaped associations between the domestic physical activity and new-onset hypertension in both males and females (both P values for nonlinearity < .001). Consistently, when domestic physical activity was assessed as categories (<10, 10 -< 20, 20 -< 30, 30 -< 40, 40 -< 50, 50 -< 60, 60 -<70, 70 -< 80, 80 -< 90, 90 -< 100, ≥100 MET-hours/week), compared with those with domestic physical activity < 10 MET-hours/week, the lower and similar risks of new-onset hypertension were found in participants with domestic physical activity 30 -< 90 MET-hours/week in both males and females.
Moderate domestic physical activity was associated with a lower risk of new-onset hypertension among both males and females.
国内体力活动与高血压之间的关系尚不确定。我们旨在评估中国男性和女性中，国内体力活动与新发高血压之间的前瞻性关系。
共有 9254 名成年人在基线时无高血压，他们来自中国健康与营养调查。通过使用自我报告的问卷获得国内体力活动数据，并计算为代谢当量任务（MET）-小时/周。MET 小时/周可以同时考虑活动的强度和时间。研究结果为新发高血压，定义为收缩压≥140mmHg 或舒张压≥90mmHg 或由医生诊断或在随访期间接受降压治疗。
在 81996 人年的随访中，共有 2892 名参与者发生了高血压。总体而言，男性和女性的国内体力活动与新发高血压之间呈反向 J 形关联（两者的非线性 P 值均<0.001）。一致地，当国内体力活动被评估为以下类别时（<10、10-<20、20-<30、30-<40、40-<50、50-<60、60-<70、70-<80、80-<90、90-<100、≥100 MET-小时/周），与每周国内体力活动<10MET-小时相比，男性和女性中每周国内体力活动为 30-<90MET-小时的参与者发生新发高血压的风险较低且相似。
适度的国内体力活动与男性和女性新发高血压的风险降低有关。
