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德国女孩的人乳头瘤病毒(HPV)疫苗接种。横断面KiGGS第二轮研究结果及趋势

Human papillomavirus (HPV) vaccination of girls in Germany. Results of the cross-sectional KiGGS Wave 2 study and trends.

作者信息

Poethko-Müller Christina, Buttmann-Schweiger Nina, Takla Anja

机构信息

Robert Koch Institute, Berlin, Department of Epidemiology and Health Monitoring.

Robert Koch Institute, Berlin, Department of Infectious Disease Epidemiology.

出版信息

J Health Monit. 2018 Dec 12;3(4):79-86. doi: 10.17886/RKI-GBE-2018-102.2. eCollection 2018 Dec.

Abstract

Since 2007, the Standing Committee on Vaccination (STIKO) has recommended that all girls receive vaccinations against the human papillomavirus (HPV) in order to reduce the disease burden of cervical cancer. Persistent infections with high-risk HPV subtypes increase a woman's risk of developing cancer. In the second wave of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS Wave 2, 2014-2017), 42% of 2,958 11- to 17-year-old girls reported that they had received at least one HPV vaccination, and 31.4% reported a full HPV vaccination. 45.3% of 14- to 17-year-old girls reported a complete series of HPV vaccinations. Compared to the figures reported in KiGGS Wave 1 five years ago, HPV vaccination coverage has therefore remained stable. A vaccination coverage below 50% in girls is too low to exploit the potential of HPV vaccination to reduce cervical cancer rates in Germany.

摘要

自2007年以来,德国疫苗接种常务委员会(STIKO)建议所有女孩接种人乳头瘤病毒(HPV)疫苗,以减轻宫颈癌的疾病负担。高危HPV亚型的持续感染会增加女性患癌风险。在德国儿童和青少年健康访谈与检查调查的第二轮(KiGGS第二轮,2014 - 2017年)中,2958名11至17岁女孩中有42%报告称她们至少接种过一剂HPV疫苗,31.4%报告称已完成HPV全程接种。14至17岁女孩中有45.3%报告称已完成HPV系列接种。因此,与五年前KiGGS第一轮报告的数据相比,HPV疫苗接种覆盖率保持稳定。德国女孩中低于50%的疫苗接种覆盖率过低,无法充分发挥HPV疫苗在降低宫颈癌发病率方面的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c192/8852778/8b708e70dbce/johm-3-4-79-g001.jpg

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