Remschmidt Cornelius, Walter Dietmar, Schmich Patrick, Wetzstein Matthias, Deleré Yvonne, Wichmann Ole
a Immunization Unit; Robert Koch Institute ; Berlin , Germany.
Hum Vaccin Immunother. 2014;10(9):2527-35. doi: 10.4161/21645515.2014.970920. Epub 2014 Oct 30.
Many industrialized countries have introduced human papillomavirus (HPV) vaccination of young women, but vaccine uptake often remains suboptimal. This study aimed to investigate whether a social media site like Facebook is an appropriate tool to assess knowledge, attitude and uptake related to HPV vaccination in young women in Germany.
Between December 2012 and January 2013 two different targeting strategies were implemented on Facebook, providing a link to an online questionnaire. Advertisements were displayed to female Facebook users aged 18-25 years living in Germany. During the simple targeting strategy, advertisements comprised health-related images along with various short titles and text messages. During the focused strategy, advertisements were targeted to users who in addition had certain fashion brands or pop stars listed on their profiles. The targeting strategies were compared with respect to participant characteristics. Univariate and multivariate analyses were used to identify factors associated with HPV vaccine uptake.
A total of 1161 women participated. The two targeting strategies resulted in significant differences regarding educational status and migrant background. Overall, awareness of HPV was high, but only 53% received at least one vaccine dose. In multivariate analysis, HPV vaccine uptake was independently associated with a physician's recommendation and trust in vaccine effectiveness. Concerns of adverse effects were negatively associated with vaccine uptake.
Social network recruitment permits fast and convenient access to young people. Sample characteristics can be manipulated by adjusting targeting strategies. There is further need for promoting knowledge of HPV vaccination among young women. Physicians have a major role in the vaccination decision-making process of young women.
许多工业化国家已推行针对年轻女性的人乳头瘤病毒(HPV)疫苗接种,但疫苗接种率往往仍不理想。本研究旨在调查像脸书这样的社交媒体网站是否是评估德国年轻女性与HPV疫苗接种相关的知识、态度和接种率的合适工具。
2012年12月至2013年1月期间,在脸书上实施了两种不同的定向策略,提供了一个在线问卷的链接。向居住在德国的18至25岁女性脸书用户展示广告。在简单定向策略中,广告包括与健康相关的图片以及各种简短标题和短信。在聚焦策略中,广告针对的是那些在其个人资料中还列出了某些时尚品牌或流行歌星的用户。比较了两种定向策略的参与者特征。采用单因素和多因素分析来确定与HPV疫苗接种相关的因素。
共有1161名女性参与。两种定向策略在教育程度和移民背景方面存在显著差异。总体而言,HPV的知晓率较高,但只有53%的人至少接种了一剂疫苗。在多因素分析中,HPV疫苗接种与医生的建议以及对疫苗有效性的信任独立相关。对不良反应的担忧与疫苗接种呈负相关。
通过社交网络招募可以快速方便地接触到年轻人。可以通过调整定向策略来控制样本特征。进一步需要提高年轻女性对HPV疫苗接种的认识。医生在年轻女性的疫苗接种决策过程中起着主要作用。