Rehabilitation Medicine Center, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China.
Department of Rehabilitation, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China.
Pain Res Manag. 2022 May 9;2022:9939891. doi: 10.1155/2022/9939891. eCollection 2022.
Although there are many pharmacological interventions for adults with osteoarthritis (OA) who do not meet the indications for surgery, side effects and adverse effects cannot be ignored. Physical interventions are known for their effectiveness and safety, and pulsed electromagnetic fields (PEMFs) have already been applied to skeletal diseases such as osteoporosis.
In this systematic review and meta-analysis, we aimed to assess the efficacy of PEMF on the major symptoms of patients with OA compared with efficacy of other interventions.
Randomized controlled trials (RCTs) investigating OA patients treated with PEMF and with pain, stiffness, and physical function impairment since 2009 were included. The Visual Analog Scale (VAS) and Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) scores were used for assessment. All extracted data were analyzed using RevMan V.5.3.
Eleven RCTs consisting of 614 patients were enrolled in this meta-analysis, of which 10 trials comprised knee OA and one comprised hand OA. Compared with the control groups, the PEMF treatment yielded a more favorable output. PEMF alleviated pain (standardized mean differences [SMD] = 0.71, 95% confidence interval [CI]: 0.08-1.34, = 0.03), improved stiffness (SMD = 1.34, 95% CI: 0.45-2.23,=0.003), and restored physical function (SMD = 1.52, 95% CI: 0.49-2.55,=0.004).
PEMF therapy ameliorates OA symptoms such as pain, stiffness, and physical function in patients compared to other conservative treatments. There is an urgent need to search for different types of OA in multiple locations.
虽然有许多针对不符合手术指征的骨关节炎（OA）成人的药理学干预措施，但副作用和不良反应不容忽视。物理干预以其有效性和安全性而闻名，脉冲电磁场（PEMF）已应用于骨质疏松等骨骼疾病。
在这项系统评价和荟萃分析中，我们旨在评估 PEMF 对 OA 患者主要症状的疗效，与其他干预措施的疗效进行比较。
纳入了自 2009 年以来使用 PEMF 治疗 OA 患者的随机对照试验（RCT），这些患者存在疼痛、僵硬和身体功能障碍。使用视觉模拟评分（VAS）和西部安大略省麦克马斯特大学骨关节炎指数（WOMAC）评分进行评估。所有提取的数据均使用 RevMan V.5.3 进行分析。
共有 11 项 RCT 纳入了本荟萃分析，共包括 614 名患者，其中 10 项研究涉及膝关节 OA，1 项研究涉及手部 OA。与对照组相比，PEMF 治疗的效果更为有利。PEMF 减轻疼痛（标准化均数差 [SMD] = 0.71，95%置信区间 [CI]：0.08-1.34，=0.03），改善僵硬（SMD = 1.34，95% CI：0.45-2.23，=0.003），并恢复身体功能（SMD = 1.52，95% CI：0.49-2.55，=0.004）。
与其他保守治疗相比，PEMF 疗法可改善 OA 患者的疼痛、僵硬和身体功能等症状。迫切需要在多个部位搜索不同类型的 OA。
