Cheng Jun, Yu Yanling, Ma Qiongjin, Wang Zhijian, Zhou Qingrong, Zhang Guolong, Hou Shuangyi, Zhou Lin, Liu Feiying, Xia Lan, Xu Lin, Zhang Canyou, Xia Yinyin, Chen Hui, Zhang Hui, Wang Lixia
National Center for Tuberculosis Control and Prevention, China CDC, Beijing, China.
Heilongjiang Provincial Center for Disease Control and Prevention, Harbin, Heilongjiang, China.
China CDC Wkly. 2022 Jan 21;4(3):41-46. doi: 10.46234/ccdcw2022.004.
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: The association of diabetes mellitus (DM) with both increased risk of tuberculosis (TB) and unfavorable treatment outcomes has been identified by many studies (1). However, epidemic data for TB cases in DM patients is absent in China.
WHAT IS ADDED BY THIS REPORT?: This current population-based prospective cohort study, conducted in ten counties located in eastern, central, and western China during 2013-2015, revealed a high prevalence and incidence of TB in known DM patients. Most TB cases were captured by active case-finding and a much higher presence of being asymptomatic among TB/DM patients was obtained.
WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Active case-finding should be carried out in DM patients and populations at high risk for developing TB. A TB symptom screening-based case-finding strategy is not enough; chest radiography check should be done once a year for these patients.
许多研究已证实糖尿病（DM）与结核病（TB）风险增加及不良治疗结局相关（1）。然而，中国缺乏糖尿病患者结核病病例的流行数据。
这项基于人群的前瞻性队列研究于2013年至2015年在中国东部、中部和西部的十个县开展，结果显示已知糖尿病患者中结核病的患病率和发病率很高。大多数结核病病例是通过主动病例发现捕获的，并且结核病/糖尿病患者中无症状者的比例更高。
应在糖尿病患者及结核病高危人群中开展主动病例发现。仅基于结核病症状筛查的病例发现策略是不够的；这些患者应每年进行一次胸部X光检查。
