Graham W G, Bradley D A
N Engl J Med. 1978 Sep 21;299(12):624-7. doi: 10.1056/NEJM197809212991203.
We undertook a randomized clinical trial to evaluate the efficacy of chest physiotherapy and intermittent positive-pressure breathing in the treatment of pneumonia. The diagnosis of pneumonia required a compatible clinical history and x-ray confirmation. A total of 54 patients were assigned to treatment and control groups and were similar in age, smoking history, underlying lung disease and prior antibiotic treatment. Antibiotic therapy, guided by Gram stain and sputum and blood cultures, was similar in both groups. Chest physiotherapy, consisting of postural drainage, percussion and vibration, was given concurrently with intermittent positive-pressure breathing with use of racemic epinephrine every four hours. There was no statistically significant difference in duration of fever, extent of radiographic clearing, duration of hospital stay and mortality between the control and treated groups. Chest physiotherapy and intermittent positive-pressure breathing do not hasten the resolution of pneumonia.
我们进行了一项随机临床试验，以评估胸部物理治疗和间歇性正压通气治疗肺炎的疗效。肺炎的诊断需要符合临床病史并经X光确认。共有54名患者被分配到治疗组和对照组，两组在年龄、吸烟史、潜在肺部疾病和先前的抗生素治疗方面相似。两组均在革兰氏染色、痰液和血培养的指导下进行抗生素治疗，治疗方式相似。胸部物理治疗包括体位引流、叩击和振动，每四小时与使用消旋肾上腺素的间歇性正压通气同时进行。对照组和治疗组在发热持续时间、影像学清除程度、住院时间和死亡率方面没有统计学上的显著差异。胸部物理治疗和间歇性正压通气并不能加速肺炎的痊愈。
