Do Quan, Lipatov Kirill, Ramar Kannan, Rasmusson Jenna, Pickering Brian W, Herasevich Vitaly
From the Department of Anesthesiology and Perioperative Medicine.
Division of Pulmonary and Critical Care Medicine.
J Patient Saf. 2022 Oct 1;18(7):e1083-e1089. doi: 10.1097/PTS.0000000000001013. Epub 2022 May 19.
Analyzing pressure injury (PI) risk factors is complex because of multiplicity of associated factors and the multidimensional nature of this injury. The main objective of this study was to identify patients at risk of developing PI.
Prediction performances of multiple popular supervised learning were tested. Together with the typical steps of a machine learning project, steps to prevent bias were carefully conducted, in which analysis of correlation covariance, outlier removal, confounding analysis, and cross-validation were used.
The most accurate model reached an area under receiver operating characteristic curve of 99.7%. Ten-fold cross-validation was used to ensure that the results were generalizable. Random forest and decision tree had the highest prediction accuracy rates of 98%. Similar accuracy rate was obtained on the validation cohort.
We developed a prediction model using advanced analytics to predict PI in at-risk hospitalized patients. This will help address appropriate interventions before the patients develop a PI.
由于压力性损伤(PI)相关因素的多样性以及该损伤的多维度性质,对其风险因素进行分析较为复杂。本研究的主要目的是识别有发生PI风险的患者。
测试了多种流行的监督学习的预测性能。与机器学习项目的典型步骤一起,仔细进行了预防偏差的步骤,其中使用了相关协方差分析、异常值去除、混杂分析和交叉验证。
最准确的模型在受试者工作特征曲线下的面积达到99.7%。使用十折交叉验证以确保结果具有普遍性。随机森林和决策树的预测准确率最高,为98%。在验证队列中获得了相似的准确率。
我们使用高级分析方法开发了一个预测模型,以预测高危住院患者的PI。这将有助于在患者发生PI之前采取适当的干预措施。