Byeon Jeong Hoon, Kim Young-Woo
Department of Chemistry, Purdue University, Indiana 47907, United States.
Department of Automotive Engineering, Hoseo University, Asan 336-795, Republic of Korea.
ACS Macro Lett. 2014 Feb 18;3(2):205-210. doi: 10.1021/mz500006k. Epub 2014 Feb 5.
We report the development of Ag nanodendrites where ultrafine Pd particles served as seeds for the subsequent deposition of Ag on their surfaces. By applying chitosan as both a reductant and a stabilizer, chitosan-conjugated Ag dendritic nanopowders were continuously synthesized using a serial system consisting of a spark discharge, an ultrasound-assisted polyol cell, and a collison atomizer with a heated tubular reactor. The resulting materials were then employed to kill cancerous cells photothermally. A spark discharge between Pd electrodes was employed to vaporize Pd components into a N flow, and finally Pd particles were injected into an ultrasound irradiating Ag polyol cell to initiate Ag deposition on incoming Pd primary particles (∼4 nm in lateral dimension). The chitosan-conjugated Ag nanodendrites (∼240 nm in lateral dimension) were formed through collison atomization, and the nanodendrites were employed as sensitizers for photothermal cancerous cell killing under near-infrared irradiation in vitro.
我们报道了银纳米枝晶的制备，其中超细钯颗粒作为种子，用于后续银在其表面的沉积。通过将壳聚糖用作还原剂和稳定剂，使用由火花放电、超声辅助多元醇池和带有加热管式反应器的碰撞雾化器组成的串联系统，连续合成了壳聚糖共轭的银树枝状纳米粉末。然后将所得材料用于光热杀死癌细胞。在钯电极之间进行火花放电，将钯成分蒸发到氮气流中，最后将钯颗粒注入超声辐照的银多元醇池中，以引发银在进入的钯初级颗粒（横向尺寸约4纳米）上的沉积。通过碰撞雾化形成壳聚糖共轭的银纳米枝晶（横向尺寸约240纳米），并且这些纳米枝晶在体外近红外照射下用作光热杀死癌细胞的敏化剂。
