Osteoarthritis: A complicated joint disease requiring extensive studies with multiple approaches.
作者信息
Chen Di
机构信息
Faculty of Pharmaceutical Sciences, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
出版信息
J Orthop Translat. 2022 Mar 22;32:130. doi: 10.1016/j.jot.2022.02.009. eCollection 2022 Jan.
Abstract
摘要
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Molecular signaling in temporomandibular joint osteoarthritis.颞下颌关节骨关节炎中的分子信号传导
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Associations of osteoclastogenesis and nerve growth in subchondral bone marrow lesions with clinical symptoms in knee osteoarthritis.膝关节骨关节炎软骨下骨髓损伤中破骨细胞生成与神经生长的关联及其与临床症状的关系
J Orthop Translat. 2021 Dec 1;32:69-76. doi: 10.1016/j.jot.2021.11.002. eCollection 2022 Jan.
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Anti-hypertrophic effect of synovium-derived stromal cells on costal chondrocytes promotes cartilage repairs.滑膜来源的基质细胞对肋软骨细胞的抗肥大作用促进软骨修复。
J Orthop Translat. 2021 Jun 2;32:59-68. doi: 10.1016/j.jot.2021.05.002. eCollection 2022 Jan.
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Bilayered scaffold with 3D printed stiff subchondral bony compartment to provide constant mechanical support for long-term cartilage regeneration.具有3D打印硬软骨下骨腔室的双层支架，为长期软骨再生提供持续的机械支撑。
J Orthop Translat. 2021 Oct 12;30:112-121. doi: 10.1016/j.jot.2021.09.001. eCollection 2021 Sep.
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Cyclooxygenase-2 regulates PTHrP transcription in human articular chondrocytes and is involved in the pathophysiology of osteoarthritis in rats.环氧化酶-2调节人关节软骨细胞中甲状旁腺激素相关蛋白的转录，并参与大鼠骨关节炎的病理生理过程。
J Orthop Translat. 2021 Aug 12;30:16-30. doi: 10.1016/j.jot.2021.06.003. eCollection 2021 Sep.
6
Combination of chondrocytes and chondrons improves extracellular matrix production to promote the repairs of defective knee cartilage in rabbits.软骨细胞与软骨粒的组合可改善细胞外基质的产生，以促进兔膝关节软骨缺损的修复。
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Runx2 plays a central role in Osteoarthritis development.Runx2在骨关节炎发展过程中起核心作用。
J Orthop Translat. 2019 Dec 23;23:132-139. doi: 10.1016/j.jot.2019.11.008. eCollection 2020 Jul.
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Multiple umbilical cord-derived MSCs administrations attenuate rat osteoarthritis progression via preserving articular cartilage superficial layer cells and inhibiting synovitis.多次给予脐带间充质干细胞可通过保护关节软骨表层细胞和抑制滑膜炎来减轻大鼠骨关节炎的进展。
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Acute Synovitis after Trauma Precedes and is Associated with Osteoarthritis Onset and Progression.创伤后急性滑膜炎先于并与骨关节炎发病和进展相关。
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Osteoarthritis: toward a comprehensive understanding of pathological mechanism.骨关节炎：迈向对病理机制的全面理解
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