Department of Psychiatry, Hospital Universitario de Navarra, Pamplona, Spain; Instituto de Investigación Sanitaria de Navarra (IdiSNa), Pamplona, Spain.
Instituto de Investigación Sanitaria de Navarra (IdiSNa), Pamplona, Spain; Mental Health Department, Servicio Navarro de Salud-Osasunbidea, Pamplona, Spain.
Schizophr Res. 2022 Jun;244:46-54. doi: 10.1016/j.schres.2022.05.005. Epub 2022 May 17.
Network analysis is an important conceptual and analytical approach in mental health research. However, few studies have used network analysis to examine the structure of cognitive performance in psychotic disorders. We examined the network structure of the cognitive scores of a sample of 207 first-episode psychosis (FEP) patients and 188 healthy controls. Participants were assessed using a battery of 10 neuropsychological tests. Fourteen cognitive scores encompassing six cognitive domains and premorbid IQ were selected to perform the network analysis. Many similarities were found in the network structure of FEP patients and healthy controls. Verbal memory, attention, working memory and executive function nodes were the most central nodes in the network. Nodes in both groups corresponding to the same tests tended to be strongly connected. Verbal memory, attention, working memory and executive function were central dimensions in the cognitive network of FEP patients and controls. These results suggest that the interplay between these core dimensions is essential for demands to solve complex tasks, and these interactions may guide the aims of cognitive rehabilitation. Network analysis of cognitive dimensions might have therapeutic implications that deserve further research.
网络分析是心理健康研究中的一个重要概念和分析方法。然而，很少有研究使用网络分析来检查精神病性障碍认知表现的结构。我们研究了 207 名首发精神病（FEP）患者和 188 名健康对照者样本的认知评分的网络结构。参与者使用一系列 10 项神经心理学测试进行评估。选择了包含六个认知领域和前摄智商的 14 项认知评分来进行网络分析。在 FEP 患者和健康对照组的网络结构中发现了许多相似之处。言语记忆、注意力、工作记忆和执行功能节点是网络中的最核心节点。两组中对应于相同测试的节点往往有很强的连接。言语记忆、注意力、工作记忆和执行功能是 FEP 患者和对照组认知网络的核心维度。这些结果表明，这些核心维度之间的相互作用对于解决复杂任务的要求至关重要，这些相互作用可能指导认知康复的目标。认知维度的网络分析可能具有治疗意义，值得进一步研究。
