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重新审视三岁前后儿童自闭症早期干预途径:一项随机对照试验

Reexamining Pathways Early Autism Intervention in Children Before and After the Third Birthday: A Randomized Control Trial.

机构信息

Callier Center for Communication Disorders, School of Behavioral and Brain Sciences, University of Texas at Dallas, 1966 Inwood Road, Dallas, TX, 75235, USA.

出版信息

J Autism Dev Disord. 2023 Mar;53(3):1189-1201. doi: 10.1007/s10803-022-05599-8. Epub 2022 May 21.

DOI:10.1007/s10803-022-05599-8
PMID:35596830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9123830/
Abstract

We reexamined the efficacy of Pathways early autism intervention using generalized measures of social communication and language skills administered by an unfamiliar adult in a novel environment. Generalized measures improve on sources of measurement bias. Sixty-seven autistic children blocked on age (under versus over 3 years) were randomly assigned to 15 weeks of Pathways or services-as-usual. Age moderated the effects of Pathways for social communication. Specifically, Pathways had a significantly large effect for children under 3 and a small effect that approached significance for children over 3. Pathways also had a small effect on expressive speech/language skills. Results replicate previous findings of the efficacy of Pathways on proximal and distal skills and support the importance of early intervention.

摘要

我们使用不熟悉的成年人在新颖环境中进行的社会沟通和语言技能的广义衡量标准,重新检查了早期自闭症途径干预的效果。广义衡量标准改善了测量偏差的来源。67 名自闭症儿童按年龄分组(3 岁以下和 3 岁以上),随机分配接受 15 周的途径治疗或常规服务。年龄对途径治疗的社会沟通效果产生了调节作用。具体来说,途径治疗对 3 岁以下的儿童有显著的大效果,对 3 岁以上的儿童则有接近显著的小效果。途径治疗对表达性言语/语言技能也有小的影响。研究结果复制了之前关于途径治疗对近端和远端技能的有效性的发现,并支持早期干预的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6170/9123830/7f0e050e55d1/10803_2022_5599_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6170/9123830/5e9d5e6ee3fb/10803_2022_5599_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6170/9123830/7f0e050e55d1/10803_2022_5599_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6170/9123830/5e9d5e6ee3fb/10803_2022_5599_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6170/9123830/7f0e050e55d1/10803_2022_5599_Fig2_HTML.jpg

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