Yang Lixiang, Chen Yuanyuan, Lou Fei, Zhao Xiaoxia, Zhou Jia
Department of Cardiology, Hangzhou Fuyang Hospital of Traditional Chinese Medicine, Hangzhou, China.
Department of Geriatrics, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.
Cardiol Res Pract. 2022 May 12;2022:5408063. doi: 10.1155/2022/5408063. eCollection 2022.
The treatment of chronic stable heart failure (CSHF) with integrated traditional Chinese and Western medicine has been of wide concern. We mainly discuss the clinical efficacy of TCM decoction combined with acupuncture and moxibustion (A&M) in CSHF treatment on the basis of syndrome differentiation and treatment (SDT). The control group was given conventional cardiac rehabilitation (CCR), and the treatment group was given TCM decoction combined with A&M treatment based on SDT on the basis of conventional cardiac rehabilitation. The clinical efficacy and cardiopulmonary exercise testing (CPET) indicators were evaluated. Left ventricular ejection fraction (LVEF), NT-proBNP, myocardial ischemia threshold (MIT), and 6-minute walking distance (6MWD) were measured by ultrasound, ELISA, electrocardiogram, and 6MWD test. After treatment, the clinical efficacy, LVEF, and 6MWD of the treatment group were better than in the control group. The NT-proBNP plasma level and MIT in the treatment group were lower than in the control group. The treatment group had enhanced AT, VO Peak, VO Peak/HR, and Peak power and decreased resting systolic pressure and peak systolic pressure, and the difference was statistically significant. Dialectical comprehensive treatment of TCM could effectively improve cardiac function and clinical treatment effect, which was worthy of clinical application.
中西医结合治疗慢性稳定型心力衰竭（CSHF）已受到广泛关注。我们主要探讨在辨证论治基础上，中药汤剂联合针灸治疗CSHF的临床疗效。对照组给予常规心脏康复（CCR），治疗组在常规心脏康复基础上给予基于辨证论治的中药汤剂联合针灸治疗。评估临床疗效及心肺运动试验（CPET）指标。通过超声、酶联免疫吸附测定（ELISA）、心电图及6分钟步行距离（6MWD）测试测量左心室射血分数（LVEF）、N末端B型利钠肽原（NT-proBNP）、心肌缺血阈值（MIT）及6MWD。治疗后，治疗组的临床疗效、LVEF及6MWD均优于对照组。治疗组的NT-proBNP血浆水平及MIT低于对照组。治疗组的无氧阈（AT）、峰值摄氧量（VO₂Peak）、VO₂Peak/心率（HR）及峰值功率增强，静息收缩压及收缩压峰值降低，差异有统计学意义。中医辨证综合治疗可有效改善心功能及临床治疗效果，值得临床应用。
