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Histone Acetylation Regulator-Mediated Acetylation Patterns Define Tumor Malignant Pathways and Tumor Microenvironment in Hepatocellular Carcinoma.组蛋白乙酰化调控因子介导的乙酰化模式定义了肝细胞癌中的肿瘤恶性途径和肿瘤微环境。
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Genomic and Epigenomic Biomarkers of Immune Checkpoint Immunotherapy Response in Melanoma: Current and Future Perspectives.黑色素瘤免疫检查点免疫治疗反应的基因组和表观基因组生物标志物:现状和未来展望。
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本文引用的文献

1
EEF2K silencing inhibits tumour progression through repressing SPP1 and synergises with BET inhibitors in melanoma.EEF2K 沉默通过抑制 SPP1 抑制肿瘤进展,并与黑色素瘤中的 BET 抑制剂协同作用。
Clin Transl Med. 2022 Feb;12(2):e722. doi: 10.1002/ctm2.722.
2
The role of N6-methyladenosine mRNA in the tumor microenvironment.N6-甲基腺苷 mRNA 在肿瘤微环境中的作用。
Biochim Biophys Acta Rev Cancer. 2021 Apr;1875(2):188522. doi: 10.1016/j.bbcan.2021.188522. Epub 2021 Feb 2.
3
BET inhibitor suppresses melanoma progression the noncanonical NF-κB/SPP1 pathway.BET 抑制剂抑制黑色素瘤进展的非经典 NF-κB/SPP1 通路。
Theranostics. 2020 Sep 15;10(25):11428-11443. doi: 10.7150/thno.47432. eCollection 2020.
4
ALKBH5 regulates anti-PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment.ALKBH5 通过调节肿瘤微环境中的乳酸和抑制性免疫细胞积累来调控抗 PD-1 治疗反应。
Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20159-20170. doi: 10.1073/pnas.1918986117. Epub 2020 Aug 3.
5
Epigenetic strategies synergize with PD-L1/PD-1 targeted cancer immunotherapies to enhance antitumor responses.表观遗传策略与PD-L1/PD-1靶向癌症免疫疗法协同作用,以增强抗肿瘤反应。
Acta Pharm Sin B. 2020 May;10(5):723-733. doi: 10.1016/j.apsb.2019.09.006. Epub 2019 Sep 25.
6
Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction.强效 BRD4 抑制剂抑制癌细胞与巨噬细胞的相互作用。
Nat Commun. 2020 Apr 14;11(1):1833. doi: 10.1038/s41467-020-15290-0.
7
N6-Methyladenosine Regulates the Expression and Secretion of TGFβ1 to Affect the Epithelial-Mesenchymal Transition of Cancer Cells.N6-甲基腺苷调节 TGFβ1 的表达和分泌,影响癌细胞的上皮-间充质转化。
Cells. 2020 Jan 25;9(2):296. doi: 10.3390/cells9020296.
8
The emerging role of epigenetic therapeutics in immuno-oncology.表观遗传学治疗在肿瘤免疫治疗中的新兴作用。
Nat Rev Clin Oncol. 2020 Feb;17(2):75-90. doi: 10.1038/s41571-019-0266-5. Epub 2019 Sep 23.
9
The role of m6A RNA methylation in cancer.m6A RNA 甲基化在癌症中的作用。
Biomed Pharmacother. 2019 Apr;112:108613. doi: 10.1016/j.biopha.2019.108613. Epub 2019 Feb 19.
10
Functions and mechanisms of non-histone protein acetylation.非组蛋白蛋白乙酰化的功能和机制。
Nat Rev Mol Cell Biol. 2019 Mar;20(3):156-174. doi: 10.1038/s41580-018-0081-3.

Editorial: Epigenetic Regulation and Tumor Immunotherapy.

作者信息

Sun Hongyin, Huang Bihui, Cao Jian, Yan Qin, Yin Mingzhu

机构信息

Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, China.

Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.

出版信息

Front Oncol. 2022 May 5;12:893157. doi: 10.3389/fonc.2022.893157. eCollection 2022.

DOI:10.3389/fonc.2022.893157
PMID:35600405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9117615/
Abstract
摘要