Zou Yi-Hua, She Kai-Qin, Ren Jia-Ning, Liang Ting-Yi, Fei Ping, Xu Yu, Li Jing, Zhang Xiang, Peng Jie, Zhao Pei-Quan
Department of Ophthalmology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China.
Int J Ophthalmol. 2022 May 18;15(5):766-772. doi: 10.18240/ijo.2022.05.12. eCollection 2022.
To determine the anatomic and visual outcomes of prophylactic juxtapapillary laser photocoagulation treatment alone in the prevention of retinal detachment (RD) in a cohort of pediatric patients diagnosed with morning glory syndrome (MGS).
A total of 24 eyes of 22 consecutive patients aged 0-15y diagnosed with MGS treated with prophylactic juxtapapillary laser photocoagulation alone were reviewed. Data including demographics, ocular examination, anatomic and visual outcomes, following treatment and complications were collected.
Two patients had bilateral laser treatment and 20 had monocular laser treatment. The age at treatment of 13 (59.1%) patients was less than 12mo. The presenting symptoms included strabismus (6/22, 27.3%), decreased vision (2/22, 9.1%), and routine fundus screening (14/22, 63.6%). Fifteen (68.2%) patients underwent cranial magnetic resonance imaging (MRI) examinations, and 3 of those 15 (20.0%) had abnormal findings in the nervous system. Based on preoperative wide-field fundus photography and B-scan echography, all (100.0%) eyes had no obvious RD. On postoperative 1mo and 6mo and the following follow-ups, the anatomic outcomes of all eyes remained stable. The mean follow-up duration was 27.7±17.5mo. No severe complications were found. Preoperative visual acuity acquired from 2 (9.1%) patients ranged from light perception to 20/200. Postoperative acuity acquired from 11 (50.0%) patients ranged from light perception to 20/125.
The preliminary anatomic and visual outcomes of prophylactic juxtapapillary laser treatment alone in pediatric MGS patients are relatively stable in a short-term follow-up. Further long-term clinical observation will be needed to confirm its efficacy and safety.
确定单纯预防性视乳头旁激光光凝治疗对一组诊断为牵牛花综合征（MGS）的儿科患者预防视网膜脱离（RD）的解剖学和视觉效果。
回顾了22例连续诊断为MGS的0至15岁患者，共24只眼，仅接受预防性视乳头旁激光光凝治疗。收集了包括人口统计学、眼部检查、治疗后解剖学和视觉效果以及并发症的数据。
2例患者接受了双侧激光治疗，20例接受了单眼激光治疗。13例（59.1%）患者治疗时年龄小于12个月。就诊症状包括斜视（6/22，27.3%）、视力下降（2/22，9.1%）和常规眼底筛查（14/22，63.6%）。15例（68.2%）患者接受了头颅磁共振成像（MRI）检查，其中15例中的3例（20.0%）神经系统检查有异常发现。根据术前广角眼底照相和B超检查，所有（100.0%）眼均无明显RD。术后1个月、6个月及后续随访中，所有眼的解剖学结果均保持稳定。平均随访时间为27.7±17.5个月。未发现严重并发症。2例（9.1%）患者术前视力从光感至20/200。11例（50.0%）患者术后视力从光感至20/125。
在短期随访中，单纯预防性视乳头旁激光治疗儿科MGS患者的初步解剖学和视觉效果相对稳定。需要进一步进行长期临床观察以确认其疗效和安全性。
