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幕下受累的自身免疫性胶质纤维酸性蛋白星形细胞病的MRI表现:病例报告

MRI findings of autoimmune glial fibrillary acidic protein astrocytopathy involving infratentorial: Case report.

作者信息

Ma Wenhui, Huang Cong, Yang Lu, Luo Junde

机构信息

Department of Radiology, No. 926 Hospital, Joint Logistics Support Force of PLA, Kaiyuan, Yunnan 661699, China.

出版信息

Radiol Case Rep. 2022 May 12;17(7):2515-2518. doi: 10.1016/j.radcr.2022.04.032. eCollection 2022 Jul.

Abstract

Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is a new type of autoimmune astrocytopathy first defined in 2016. Lack of clinical understanding, often misdiagnosed as optic neuromyelitis or multiple sclerosis. We report the clinical and MRI findings of an elderly patient with autoimmune glial fibrillary acidic protein astrocytopathy. With intractable vomiting as the first symptom, the brainstem showed typical vascular enhancement. GFAP-A lacks specificity in clinical and MRI scans. When enhancement reveals paraventricular "vascular-like enhancement" or central spinal cord tubular enhancement, it is important to consider the possibility of this disease.

摘要

自身免疫性胶质纤维酸性蛋白星形细胞病(GFAP-A)是2016年首次定义的一种新型自身免疫性星形细胞病。由于临床认识不足,常被误诊为视神经脊髓炎或多发性硬化症。我们报告了一例自身免疫性胶质纤维酸性蛋白星形细胞病老年患者的临床和MRI表现。以顽固性呕吐为首发症状,脑干显示典型的血管强化。GFAP-A在临床和MRI扫描中缺乏特异性。当强化显示脑室旁“血管样强化”或脊髓中央管状强化时,考虑本病的可能性很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7582/9114157/b11799bd409e/gr1.jpg

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