Zhu Yingming, Yao Ting, Wang Yan, Zhao Ziliang, Yang Xiaowei, Liu Xia, Zhao Guangwei
Department of Veterinary Medicine, College of Veterinary Medicine, Southwest University, Chongqing, China.
Animal, Plant and Food Test Center of Shanghai Customs, Shanghai Pudong District, Shanghai, China.
Vet Res Forum. 2022 Mar;13(1):141-144. doi: 10.30466/vrf.2021.138797.3086. Epub 2022 Mar 15.
, a newly virulent zoonotic pathogen belonging to the genus is the causative organism of emerging intra-abdominal infection, acute skin ulceration, rotten limbs and ascites in humans and animals The global spread of entails severe economic impact. However, it was rarely reported as a cause of infection and no reports were found that isolated from clinical samples. The isolate was identified as a strain by 16S rDNA amplification and DNA sequencing identification method. Even if co-infection by other bacteria could not be ruled out, this is the first report of acute disease caused by in the Chinese giant salamander in China. By using the Kirby-Bauer disc diffusion method, the sensitivity of the isolate to clinical antibiotics was evaluated. Antibiotic susceptibility test indicated that the isolate was resistant to 32 antibacterial drugs such as kanamycin, florfenicol and ceftriaxone suggesting that the isolate was a multi-drug resistant strain.
一种新出现的高致病性人畜共患病原体，属于该属，是人类和动物中新兴的腹腔内感染、急性皮肤溃疡、肢体腐烂和腹水的致病生物。该病原体的全球传播带来了严重的经济影响。然而，它很少被报道为感染原因，也未发现从临床样本中分离出该病原体的报告。通过16S rDNA扩增和DNA测序鉴定方法，该分离株被鉴定为某菌株。即使不能排除其他细菌的共感染，但这是中国大鲵中由该病原体引起急性疾病的首次报告。通过使用 Kirby-Bauer 纸片扩散法，评估了该分离株对临床抗生素的敏感性。药敏试验表明，该分离株对卡那霉素、氟苯尼考和头孢曲松等32种抗菌药物耐药，表明该分离株是多重耐药菌株。
