Laboratoire d'Écologie Microbienne, FSNV, Université de Bejaia, Bejaia, 06000, Algeria.
Laboratoire de santé publique du Québec, Institut national de santé publique du Québec, Sainte-Anne-de-Bellevue, QC, Canada.
Eur J Clin Microbiol Infect Dis. 2017 Aug;36(8):1353-1362. doi: 10.1007/s10096-017-2962-3. Epub 2017 Mar 15.
Shewanella spp. are commonly known as environmental bacteria and are most frequently isolated from aquatic areas. Currently, diseases syndromes and multidrug resistance have increasingly been reported in the genus Shewanella. Some species are associated with various infections, such as skin and soft tissue infections, as well as bacteremia. Generally, these bacteria are opportunistic and mostly affect people with an impaired immune system. This genus is also a probable vehicle and progenitor of antibiotic resistance genes. In fact, several resistance genes and mobile genetic elements have been identified in some resistant species isolated from environmental or clinical settings. These genes confer resistance to different antibiotic classes, including those used in therapies such as β-lactams and quinolones, and are generally located on the chromosome. Recently, a multidrug-resistant (MDR) plasmid harboring several drug resistance genes associated with transposons and integrons has been identified in Shewanella xiamenensis. These antibiotic resistance genes can circulate in the environment and contribute to the emergence of antibiotic resistance. This review describes different aspects of Shewanella, focusing on the infections caused by this genus, as well as their role in the propagation of antibiotic resistance via mobile genetic elements.
希瓦氏菌属通常被称为环境细菌，最常从水生区域分离得到。目前，希瓦氏菌属的疾病综合征和多药耐药性越来越多地被报道。一些物种与各种感染有关，如皮肤和软组织感染以及菌血症。一般来说，这些细菌是机会性的，主要影响免疫系统受损的人群。该属也是抗生素耐药基因的可能载体和前体。事实上，已经从环境或临床环境中分离出的一些耐药物种中鉴定出了几种耐药基因和可移动遗传元件。这些基因赋予了对不同抗生素类别的耐药性，包括用于治疗的β-内酰胺类和喹诺酮类抗生素，通常位于染色体上。最近，在厦门希瓦氏菌中发现了一种携带与转座子和整合子相关的多种耐药基因的多药耐药（MDR）质粒。这些抗生素耐药基因可以在环境中循环，并有助于抗生素耐药性的出现。本综述描述了希瓦氏菌的不同方面，重点介绍了该属引起的感染，以及它们通过可移动遗传元件在抗生素耐药性传播中的作用。
