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深静脉血栓形成和肺栓塞背景下小脑和枕叶梗死中的 T 波倒置提示反常栓塞:一例报告

T-wave Inversions in Cerebellar and Occipital Lobe Infarcts in the Setting of Deep Vein Thrombosis and Pulmonary Embolism Suggestive of Paradoxical Emboli: A Case Report.

作者信息

Alshamam Mohsen S, Nso Nso, Nassar Mahmoud, Idrees Zarwa, Ghernautan Victoria, Khan Saifullah, Abdalazeem Yousef, Munira Most

机构信息

Internal Medicine, Ichan School of Medicine at Mount Sinai / New York City (NYC) Health + Hospitals/Queens, New York, USA.

General Medicine, Saint James School of Medicine, St. Vincent, VCT.

出版信息

Cureus. 2022 Apr 18;14(4):e24230. doi: 10.7759/cureus.24230. eCollection 2022 Apr.

Abstract

Cardiological causes account for the majority of acute electrocardiographic (ECG) changes. The reason for this fear is the irreversibility of myocardial necrosis. Generally, various changes can be observed in the ECG, including ST-T changes, QTc prolongation, arrhythmias, and T-wave inversions. Even though T-wave inversions can be seen in myocardial ischemia/infarction, they are rarely seen in acute cerebrovascular accidents (CVAs). We present the case of a 66-year-old woman who initially presented at our facility with dizziness in the context of orthostatic hypotension. An initial cardiac evaluation revealed no cardiac involvement. She was treated with intravenous fluids (IVF), which improved her symptoms. The patient's mental status was markedly altered approximately four days after admission. In this instance, she was found to have abnormal ECG findings (not previously observed on the ECG that was obtained on the day of admission), elevated troponin T levels, as well as elevated pro-B-type natriuretic peptide (pro-BNP). The patient was given aspirin and clopidogrel immediately and was placed on a heparin drip for a suspected non-ST elevation myocardial infarction (NSTEMI). A non-contrast computed tomography of the head revealed an acute cerebrovascular accident (CVA), following which the heparin drip was stopped. The patient was then transferred to another acute care facility capable of performing neurosurgical interventions. Additionally, a computed tomography angiography (CTA) of the chest and lower extremities venous duplex showed bilateral pulmonary emboli and deep venous thrombosis (DVT), respectively.

摘要

心脏原因是急性心电图(ECG)改变的主要原因。产生这种担忧的原因是心肌坏死的不可逆性。一般来说,心电图可观察到各种变化,包括ST-T改变、QTc延长、心律失常和T波倒置。尽管T波倒置可见于心肌缺血/梗死,但在急性脑血管意外(CVA)中很少见。我们报告一例66岁女性病例,该患者最初因体位性低血压伴头晕前来我院就诊。初步心脏评估未发现心脏受累。给予静脉补液(IVF)治疗后症状改善。入院约四天后患者精神状态明显改变。此时,发现其心电图有异常表现(入院当天心电图未观察到)、肌钙蛋白T水平升高以及B型利钠肽原(pro-BNP)升高。患者立即给予阿司匹林和氯吡格雷,并因疑似非ST段抬高型心肌梗死(NSTEMI)给予肝素静脉滴注。头部非增强计算机断层扫描显示急性脑血管意外(CVA),随后停止肝素静脉滴注。然后患者被转至另一家能够进行神经外科干预的急性护理机构。此外,胸部计算机断层扫描血管造影(CTA)和下肢静脉双功超声分别显示双侧肺栓塞和深静脉血栓形成(DVT)。

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