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评估前夜接受手术的外科医生的围手术期结局。

Assessment of Perioperative Outcomes Among Surgeons Who Operated the Night Before.

机构信息

Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California.

Department of Health Policy, Stanford University School of Medicine, Stanford, California.

出版信息

JAMA Intern Med. 2022 Jul 1;182(7):720-728. doi: 10.1001/jamainternmed.2022.1563.

Abstract

IMPORTANCE

The association between physician fatigue and patient outcomes is important to understand but has been difficult to examine given methodological and data limitations. Surgeons frequently perform urgent procedures overnight and perform additional procedures the following day, which could adversely affect outcomes for those daytime operations.

OBJECTIVE

To examine the association between an attending surgeon operating overnight and outcomes for operations performed by that surgeon the next day.

DESIGN, SETTING, AND PARTICIPANTS: In this cross-sectional study, a retrospective analysis of a large multicenter registry of surgical procedures was done using a within-surgeon analysis to address confounding, with data from 20 high-volume US institutions. This study included 498 234 patients who underwent a surgical procedure during the day (between 7 am and 5 pm) between January 1, 2010, and August 30, 2020.

EXPOSURES

Whether the attending surgeon for the current day's procedures operated between 11 pm and 7 am the previous night. Two exposure measures were examined: whether the surgeon operated at all the previous night and the number of hours spent operating the previous night (including having performed no work at all).

MAIN OUTCOMES AND MEASURES

The primary composite outcome was in-hospital death or major complication (sepsis, pneumonia, myocardial infarction, thromboembolic event, or stroke). Secondary outcomes included operation length and individual outcomes of death, major complications, and minor complications (surgical site infection or urinary tract infection).

RESULTS

Among 498 234 daytime operations performed by 1131 surgeons, 13 098 (2.6%) involved an attending surgeon who operated the night before. The mean (SD) age of the patients who underwent an operation was 55.3 (16.4) years, and 264 740 (53.1%) were female. After adjusting for operation type, surgeon fixed effects, and observable patient characteristics (ie, age and comorbidities), the adjusted incidence of in-hospital death or major complications was 5.89% (95% CI, 5.41%-6.36%) among daytime operations when the attending surgeon operated the night before compared with 5.87% (95% CI, 5.85%-5.89%) among daytime operations when the same surgeon did not (absolute adjusted difference, 0.02%; 95% CI, -0.47% to 0.51%; P = .93). No significant associations were found between overnight work and secondary outcomes except for operation length. Operating the previous night was associated with a statistically significant decrease in length of daytime operations (adjusted length, 112.7 vs 117.4 minutes; adjusted difference, -4.7 minutes; 95% CI, -8.7 to -0.8, P = .02), although this difference is unlikely to be meaningful.

CONCLUSIONS AND RELEVANCE

The findings of this cross-sectional study suggest that operating overnight was not associated with worse outcomes for operations performed by surgeons the subsequent day. These results provide reassurance concerning the practice of having attending surgeons take overnight call and still perform operations the following morning.

摘要

重要性

了解医生疲劳与患者结局之间的关系很重要,但由于方法学和数据方面的限制,这一直难以研究。外科医生经常在夜间进行紧急手术,并在第二天进行其他手术,这可能会对白天手术的结果产生不利影响。

目的

研究主刀医生在夜间进行手术与次日该医生进行手术的结果之间的关联。

设计、地点和参与者:在这项横断面研究中,对来自 20 家美国大型多中心手术登记处的数据进行了回顾性分析,采用了同一医生分析来解决混杂因素,研究对象为 2010 年 1 月 1 日至 2020 年 8 月 30 日间接受日间手术的 498234 名患者。

暴露因素

当日手术的主治医生在前一天晚上 11 点至早上 7 点之间是否进行过手术。研究考察了两种暴露情况:前一天晚上是否进行过手术以及前一天晚上的手术时间(包括完全未进行手术)。

主要结局和测量指标

主要复合结局为院内死亡或主要并发症(脓毒症、肺炎、心肌梗死、血栓栓塞事件或中风)。次要结局包括手术时间以及死亡、主要并发症和次要并发症(手术部位感染或尿路感染)的个别结局。

结果

在 1131 名外科医生进行的 498234 例日间手术中,有 13098 例(2.6%)涉及前一天晚上进行手术的主治医生。接受手术的患者平均(SD)年龄为 55.3(16.4)岁,264740 例(53.1%)为女性。在调整手术类型、外科医生固定效应和可观察到的患者特征(即年龄和合并症)后,与前一天晚上没有手术的主刀医生相比,日间手术时主刀医生前一天晚上进行手术的院内死亡或主要并发症发生率为 5.89%(95%CI,5.41%-6.36%),而日间手术时主刀医生相同的情况下发生率为 5.87%(95%CI,5.85%-5.89%)(绝对调整差异,0.02%;95%CI,-0.47%至 0.51%;P=0.93)。除手术时间外,未发现夜间工作与次要结局之间存在显著关联。前一天晚上进行手术与日间手术时间明显缩短相关(调整后手术时间,112.7 分钟比 117.4 分钟;调整后差异,-4.7 分钟;95%CI,-8.7 至 -0.8,P=0.02),尽管这种差异可能没有实际意义。

结论和相关性

这项横断面研究的结果表明,夜间手术与次日外科医生进行的手术结果不佳无关。这些结果为让主治医生夜间值班并在第二天早上进行手术的做法提供了保证。

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