Vector-borne diseases, Virology Department, Animal and Plant Health Agency, Woodham Lane, Weybridge, KT15 3NB, UK.
Viral Zoonoses, Virology Department, Animal and Plant Health Agency, Woodham Lane, Weybridge, KT15 3NB, UK.
J Med Microbiol. 2022 May;71(5). doi: 10.1099/jmm.0.001502.
Louping ill virus (LIV) is a single-stranded, positive-sense RNA virus within the genus that is transmitted to vertebrate hosts by bites from infected ticks, the arthropod vector. The virus affects livestock in upland areas of Great Britain and Ireland, resulting in a febrile illness that can progress to fatal encephalitis. Prevention of the disease is facilitated by combining acaricide treatment, land management and vaccination strategies. However, vaccines have been discontinued in recent years. Although rare, LIV can be transmitted to and cause disease in humans. Consequently, LIV infection is a threat to human and veterinary health and can impact on the rural economy.
绵羊肺腺瘤病毒（LIV）是一种属内的单链、正链 RNA 病毒，通过受感染的蜱虫（节肢动物媒介）叮咬传播给脊椎动物宿主。该病毒影响大不列颠和爱尔兰高地地区的牲畜，导致发热疾病，并可能发展为致命性脑炎。通过联合杀螨剂处理、土地管理和疫苗接种策略，可以预防这种疾病。然而，近年来疫苗已被停止使用。尽管罕见，但 LIV 可传播给人类并导致疾病。因此，LIV 感染对人类和兽医健康构成威胁，并可能影响农村经济。
