估算 1998 年至 2019 年香港流感相关的败血症超额死亡率和住院负担。
Estimating excess septicaemia mortality and hospitalisation burden associated with influenza in Hong Kong, 1998 to 2019.
机构信息
WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Basildon University Hospital, Basildon, Essex, UK.
出版信息
Epidemiol Infect. 2022 Apr 27;150:e101. doi: 10.1017/S0950268822000760.
Abstract
Influenza virus infections can lead to a number of secondary complications, including sepsis. We applied linear regression models to mortality and hospital admission data coded for septicaemia from 1998 to 2019 in Hong Kong, and estimated that septicaemia was associated with an annual average excess mortality rate of 0.23 (95% CI 0.04-0.40) per 100 000 persons per year and an excess septicaemia hospitalisation rate of 1.73 (95% CI 0.94-2.50) per 100 000 persons per year. The highest excess morbidity and mortality was found in older adults and young children, and during influenza A(H3N2) epidemics.
摘要
流感病毒感染可导致多种继发性并发症，包括败血症。我们应用线性回归模型分析了 1998 年至 2019 年香港因败血症编码的死亡率和住院数据，估计败血症每年每 10 万人中与 0.23（95%CI 0.04-0.40）的平均超额死亡率和 1.73（95%CI 0.94-2.50）的超额败血症住院率相关。在老年人和幼儿以及在甲型 H3N2 流感流行期间，发病率和死亡率的最高。
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