Suklert Kamonnan, Phavichitr Nopaorn
Department of Pediatrics, Phramongkutklao Hospital, Bangkok, Thailand.
Pediatr Gastroenterol Hepatol Nutr. 2022 May;25(3):276-282. doi: 10.5223/pghn.2022.25.3.276. Epub 2022 May 9.
Infantile colic, a common functional gastrointestinal condition, causes distress and frustration in families. Its prevalence and incidence vary from community to community. The purpose of our study was to demonstrate the incidence of and factors associated with infantile colic in Thai infants.
We conducted a prospective analytic study to explore the incidence and factors associated with infantile colic in 386 Thai infants aged between one month and six months. Caregivers were interviewed using a questionnaire about infants' symptoms of colic based on the definition from the Rome IV criteria. Family background and potential precipitating factors of colic were also evaluated.
The incidence of colic in infants younger than 6 months was 6.5%. All infants' colic started within 12 weeks of life and lasted approximately 6 weeks. Sex, gestational age, birth weight, delivery route, birth order, family factors, and parental factors were not correlated with the occurrence of colic. Infants who were exclusively breastfed for the first 2 months of life had a lower incidence of infantile colic than those who were mixed- or formula-fed (odds ratio=3.0; 95% confidence intervals=1.3 to 7.2).
The incidence of infantile colic in Thai infants in our study was 6.5%, which is similar to that in other reports. Being exclusively breastfed for the first two months was the only risk factor in our cohort.
婴儿腹绞痛是一种常见的功能性胃肠疾病，给家庭带来困扰和沮丧。其患病率和发病率因社区而异。我们研究的目的是证明泰国婴儿中婴儿腹绞痛的发病率及相关因素。
我们进行了一项前瞻性分析研究，以探讨386名年龄在1个月至6个月之间的泰国婴儿中婴儿腹绞痛的发病率及相关因素。根据罗马IV标准的定义，使用问卷对照顾者进行访谈，询问婴儿的腹绞痛症状。还评估了家庭背景和腹绞痛的潜在诱发因素。
6个月以下婴儿腹绞痛的发病率为6.5%。所有婴儿的腹绞痛均在出生后12周内开始，持续约6周。性别、胎龄、出生体重、分娩方式、出生顺序、家庭因素和父母因素与腹绞痛的发生均无相关性。在出生后头2个月纯母乳喂养的婴儿，其婴儿腹绞痛的发病率低于混合喂养或配方奶喂养的婴儿（比值比=3.0；95%置信区间=1.3至7.2）。
在我们的研究中，泰国婴儿中婴儿腹绞痛的发病率为6.5%，与其他报告相似。在我们的队列中，头两个月纯母乳喂养是唯一的危险因素。
