Lekhtman A M, Lomtev N G, Modnikov O P
Med Radiol (Mosk). 1987 Mar;32(3):35-8.
Liver function was studied in 84 patients with operable stomach cancer prior to and at varying times after gastrectomy using dynamic scintigraphy with 131I-rose bengal and determination by a radioimmunoassay of bile acids in the peripheral blood. A group of patients without signs of focal lesion of the liver and a history of its diseases was examined. It was shown that disorders of hepatocytic function took place before the operation. After gastrectomy the disorders were accompanied by considerable retardation of the basal secretion of bile into the intestine. At the same time an increase in the concentration of bile acids in the peripheral blood above the discriminant level of healthy persons, i.e. over 0.5 mg/l was observed. Disorders of liver function were of long duration and persistent over 1 year after gastrectomy.
采用131I-玫瑰红动态闪烁扫描法并通过放射免疫分析法测定外周血胆汁酸，对84例可手术切除的胃癌患者在胃切除术前及术后不同时间的肝功能进行了研究。对一组无肝脏局灶性病变体征且无肝脏疾病史的患者进行了检查。结果表明，肝细胞功能紊乱在手术前就已出现。胃切除术后，这些紊乱伴随着胆汁向肠道基础分泌的显著延迟。同时，观察到外周血中胆汁酸浓度高于健康人的鉴别水平，即超过0.5mg/L。肝功能紊乱持续时间较长，胃切除术后超过1年仍持续存在。
