Senoo Keitaro, Yukawa Arito, Ohkura Takashi, Iwakoshi Hibiki, Nishimura Tetsuro, Teramukai Satoshi, Narumoto Jin, Matoba Satoaki
Department of Cardiac Arrhythmia Research and Innovation, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Geriatr Gerontol Int. 2022 Jul;22(7):505-510. doi: 10.1111/ggi.14397. Epub 2022 May 25.
In the older population, depression often occurs alongside physical illness. A cross-sectional community-based study examined the relationship between atrial fibrillation (AF), depression, and quality of life (QoL), and the impact of chest symptoms.
A total of 1364 older adults (≥65 years) who attended AF awareness symposia from July 2019 to December 2020 provided consent to participate in the study and valid questionnaire responses. Depression was assessed with the Geriatric Depression Scale (GDS)-15, and QoL with the 12-item Short-Form Health Survey (SF-12).
AF patients (n = 130) were divided into symptomatic AF (n = 87) and asymptomatic AF (n = 43) groups. Depressive state and physical component summary (PCS) and mental component summary (MCS) in the SF-12 were compared with the control group (non-AF group without chest symptoms, n = 911), extracted from the same symposium participants. The depression rate (defined as GDS-15 ≥ 10) was 9.2% in symptomatic AF patients, 2.3% in asymptomatic AF patients, and 2.7% in controls. The mean PCS and MCS in each group were 43.4 ± 10.8 and 54.8 ± 8.6, 44.6 ± 10.7 and 57.3 ± 7.3, and 48.5 ± 7.9 and 56.7 ± 6.8, respectively. Multivariate regression analysis showed that symptomatic AF patients had a higher risk of depression (odds ratio: 3.46, 95% confidence interval (CI) 1.27-8.57, P = 0.01) and poor QoL (PCS: B -3.17, 95% CI -5.05 to -1.29, P = 0.001 and MCS: B -1.80, 95% CI -3.45 to -0.16, P = 0.03) compared with controls, but asymptomatic AF patients did not.
In a cross-sectional community-based study, symptomatic AF patients were vulnerable to depression and poor QoL, but asymptomatic AF patients were not. Geriatr Gerontol Int 2022; 22: 505-510.
在老年人群中，抑郁症常与身体疾病同时出现。一项基于社区的横断面研究探讨了心房颤动（AF）、抑郁症和生活质量（QoL）之间的关系，以及胸部症状的影响。
2019年7月至2020年12月期间参加AF认知研讨会的1364名老年人（≥65岁）同意参与本研究并提供了有效的问卷回复。使用老年抑郁量表（GDS）-15评估抑郁症，使用12项简短健康调查（SF-12）评估生活质量。
AF患者（n = 130）分为有症状AF组（n = 87）和无症状AF组（n = 43）。将SF-12中的抑郁状态、身体成分总结（PCS）和心理成分总结（MCS）与对照组（无胸部症状的非AF组，n = 911）进行比较，对照组来自同一研讨会参与者。有症状AF患者的抑郁率（定义为GDS-15≥10）为9.2%，无症状AF患者为2.3%，对照组为2.7%。每组的平均PCS和MCS分别为43.4±10.8和54.8±8.6、44.6±10.7和57.3±7.3、48.5±7.9和56.7±6.8。多因素回归分析显示，与对照组相比，有症状AF患者患抑郁症的风险更高（比值比：3.46，95%置信区间（CI）1.27 - 8.57，P = 0.01）且生活质量较差（PCS：B -3.17，95%CI -5.05至-1.29，P = 0.001；MCS：B -1.80，95%CI -3.45至-0.16，P = 0.03），但无症状AF患者并非如此。
在一项基于社区的横断面研究中，有症状AF患者易患抑郁症和生活质量差，但无症状AF患者并非如此。《老年医学与老年病学国际杂志》2022年；22：505 - 510。
