Queiroz Jéssica do Nascimento, Macedo Rodrigo Cauduro Oliveira, Dos Santos Gabriela Cristina, Munhoz Samuel Vargas, Machado Carlos Leonardo Figueiredo, de Menezes Rodrigo Leal, Menzem Elisa Nascimento, Moritz Cesar Eduardo Jacintho, Pinto Ronei Silveira, Tinsley Grant M, de Oliveira Alvaro Reischak
Exercise Research Laboratory, School of Physical Education, Physiotherapy and Dance, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Department of Nutrition, University of Santa Cruz do Sul, Santa Cruz do Sul, Rio Grande do Sul, Brazil.
Br J Nutr. 2022 May 26:1-13. doi: 10.1017/S0007114522001581.
This exploratory study investigated the effects of early . delayed time-restricted eating (TRE) plus caloric restriction (CR) on body weight, body composition and cardiometabolic parameters in adults with overweight and obesity. Adults (20-40 years) were randomised to one of three groups for 8 weeks: early time-restricted eating (eTRE; 08.00-16.00) plus CR, delayed time-restricted eating (dTRE; 12.00-20.00) plus CR or only CR (CR; 08.00-20.00). All groups were prescribed a 25 % energy deficit relative to daily energy requirements. Thirteen participants completed the study in the eTRE and CR groups and eleven in the dTRE group ( 37). After the interventions, there was no significant difference between the three groups for any of the outcomes. Compared with baseline, significant decreases were observed in the body weight (eTRE group: -4·2 kg; 95 % CI, -5·6, -2·7; dTRE group: -4·8 kg; 95 % CI, -5·9, -3·7; CR: -4·0 kg; 95 % CI, -5·9, -2·1), fat mass (eTRE group: -2·9 kg; 95 % CI, -3·9, -1·9; dTRE group: -3·6 kg; 95 % CI, -4·6, -2·5; CR: -3·1 kg; 95 % CI, -4·3, -1·8) and fasting glucose levels (eTRE group: -4 mg/dl; 95 % CI, -8, -1; dTRE group: -2 mg/dl; 95 % CI, -8, 3; CR: -3 mg/dl; 95 % CI, -8, 2). In a free-living setting, TRE with a energetic deficit, regardless of the time of day, promotes similar benefits in weight loss, body composition and cardiometabolic parameters. However, given the exploratory nature of our study, further investigation is needed to confirm these findings.
这项探索性研究调查了早期、延迟限时进食（TRE）加热量限制（CR）对超重和肥胖成年人的体重、身体成分和心脏代谢参数的影响。将成年人（20 - 40岁）随机分为三组，为期8周：早期限时进食（eTRE；08:00 - 16:00）加CR、延迟限时进食（dTRE；12:00 - 20:00）加CR或仅进行CR（CR；08:00 - 20:00）。所有组均被规定相对于每日能量需求有25%的能量赤字。13名参与者完成了eTRE组和CR组的研究，11名参与者完成了dTRE组的研究（共37名）。干预后，三组在任何结果方面均无显著差异。与基线相比，体重（eTRE组：-4.2千克；95%可信区间，-5.6，-2.7；dTRE组：-4.8千克；95%可信区间，-5.9，-3.7；CR组：-4.0千克；95%可信区间，-5.9，-2.1）、脂肪量（eTRE组：-2.9千克；95%可信区间，-3.9，-1.9；dTRE组：-3.6千克；95%可信区间，-4.6，-2.5；CR组：-3.1千克；95%可信区间，-4.3，-1.8）和空腹血糖水平（eTRE组：-4毫克/分升；95%可信区间，-8，-1；dTRE组：-2毫克/分升；95%可信区间，-8，3；CR组：-3毫克/分升；95%可信区间，-8，2）均有显著下降。在自由生活环境中，无论一天中的时间如何，有能量赤字的TRE在体重减轻、身体成分和心脏代谢参数方面都能带来相似的益处。然而，鉴于我们研究的探索性质，需要进一步调查以证实这些发现。
