Khadka Bikash, Khanal Kishor
Nepal Mediciti Hospital, Lalitpur, Nepal.
J Nepal Health Res Counc. 2022 Mar 13;19(4):852-854. doi: 10.33314/jnhrc.v19i04.3803.
Guillain-Barré syndrome is an acute generalized polyneuropathy which usually follows infection with a virus or bacteria, although rarely vaccination may be associated with it. We present a case of a 44-year-man who presented with progressive weakness of both lower limbs since 6?days, neurological examination findings were consistent with flaccid-type paraplegia and investigation findings including lumbar puncture and nerve conduction studies were consistent with the diagnosis of Guillain-Barré syndrome. He had received the Johnson and Johnson corona virus disease-19 vaccine intramuscularly 15 days before his presentation. Only potential triggering factor in this case was positive finding of Jansen Vaccine. Keywords: Guillain-Barré syndrome; immunoglobulin; jansen vaccine; polyneuropathy.
吉兰-巴雷综合征是一种急性全身性多发性神经病，通常继发于病毒或细菌感染，不过疫苗接种虽很少与之相关，但也可能有关。我们报告一例44岁男性病例，该患者自6天前起出现双下肢进行性无力，神经系统检查结果符合弛缓性截瘫，包括腰椎穿刺和神经传导研究在内的检查结果与吉兰-巴雷综合征的诊断相符。他在出现症状前15天接受了强生公司的新型冠状病毒肺炎疫苗肌肉注射。该病例中唯一潜在的触发因素是扬森疫苗检测呈阳性。关键词：吉兰-巴雷综合征；免疫球蛋白；扬森疫苗；多发性神经病
