Radiology, Royal Free Hospital, London, UK
Radiology, Royal Free Hospital, London, UK.
BMJ Case Rep. 2021 Apr 22;14(4):e242956. doi: 10.1136/bcr-2021-242956.
Prevention strategies for COVID-19 transmission are at the forefront of healthcare paradigms worldwide, the main emphasis of which is vaccination. We present an interesting case of a 37-year-old man who, 3 weeks following his first dose of the chimpanzee adenovirus-vectored COVID-19 vaccine, ChAdOx1, presented to hospital with a rapidly progressive ascending muscle weakness and back pain in the absence of any other triggers. He also had a negative COVID-19 swab during admission. A diagnosis of Guillain-Barre syndrome was confirmed by correlating the clinical features with cerebrospinal fluid analysis, nerve conduction studies and MRI of the brain and whole spine. The patient received treatment with 5 days of intravenous immunoglobulin and did not require any respiratory support. He was also regularly reviewed by a multidisciplinary team consisting of neurologists, speech and language therapists, and physiotherapists and is on the course to a recovery.
预防 COVID-19 传播的策略是全球医疗保健模式的重点，其中主要强调的是疫苗接种。我们呈现了一个有趣的病例，一名 37 岁的男子，在接种第一剂 chimpanzee adenovirus-vectored COVID-19 疫苗 ChAdOx1 后 3 周，出现了迅速进展的上升性肌肉无力和背痛，没有任何其他诱因。他在入院期间的 COVID-19 拭子检测也呈阴性。通过将临床特征与脑脊液分析、神经传导研究以及脑和全脊柱 MRI 相关联，确诊为格林-巴利综合征。该患者接受了 5 天的静脉注射免疫球蛋白治疗，不需要任何呼吸支持。他还由神经科医生、言语和语言治疗师以及物理治疗师组成的多学科团队定期进行评估，并正在康复过程中。
