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发展中国家的 COVID-19 诊断方法。

COVID-19 diagnostic methods in developing countries.

机构信息

Department of Pharmacy, Faculty of Science & Engineering, Varendra University, Rajshahi, 6204, Bangladesh.

Varendra University, Rajshahi, 6204, Bangladesh.

出版信息

Environ Sci Pollut Res Int. 2022 Jul;29(34):51384-51397. doi: 10.1007/s11356-022-21041-z. Epub 2022 May 27.

DOI:10.1007/s11356-022-21041-z
PMID:35619009
原文链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9135468/
Abstract

COVID-19 has become one of the few leading causes of death and has evolved into a pandemic that disrupts everyone's routine, and balanced way of life worldwide, and will continue to do so. To bring an end to this pandemic, scientists had put their all effort into discovering the vaccine for SARS-CoV-2 infection. For their dedication, now, we have a handful of COVID-19 vaccines. Worldwide, millions of people are at risk due to the current pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2). Despite the lack of clinically authorized antiviral medications and vaccines for COVID-19, clinical trials of many recognized antiviral agents, their combination, and vaccine development in patients with confirmed COVID-19 are still ongoing. This discovery gave us a chance to get immune to this disease worldwide and end the pandemic. However, the unexpected capacity of mutation of the SARS-CoV-2 virus makes it difficult, like the recent SAS-CoV-2 Omicron variant. Therefore, there is a great necessity to spread the vaccination programs and prevent the spread of this dreadful epidemic by identifying and isolating afflicted patients. Furthermore, several COVID-19 tests are thought to be expensive, time-consuming, and require the use of adequately qualified persons to be carried out efficiently. In addition, we also conversed about how the various COVID-19 testing methods can be implemented for the first time in a developing country and their cost-effectiveness, accuracy, human resources requirements, and laboratory facilities.

摘要

COVID-19 已成为少数主要死亡原因之一,并已演变成一种大流行疾病,扰乱了全球每个人的日常生活和平衡的生活方式,并将继续这样做。为了结束这场大流行,科学家们全力以赴地发现针对 SARS-CoV-2 感染的疫苗。由于他们的奉献精神,现在我们有了一些 COVID-19 疫苗。在全球范围内,由于 SARS-CoV-2(严重急性呼吸系统综合症冠状病毒 2)引起的 2019 年冠状病毒病(COVID-19)大流行,数百万人面临风险。尽管目前针对 COVID-19 的临床批准的抗病毒药物和疫苗缺乏,但对许多已被认可的抗病毒药物及其组合的临床试验,以及针对确诊 COVID-19 患者的疫苗开发仍在进行中。这一发现使我们有机会在全球范围内对这种疾病产生免疫力并结束大流行。然而,SARS-CoV-2 病毒的突变能力出人意料,这使得情况变得困难,就像最近的 SAS-CoV-2 奥密克戎变体一样。因此,非常有必要通过识别和隔离受感染的患者来传播疫苗接种计划并防止这种可怕的传染病的传播。此外,人们认为,几种 COVID-19 检测方法既昂贵又耗时,并且需要足够合格的人员来有效地进行。此外,我们还讨论了如何在发展中国家首次实施各种 COVID-19 检测方法及其成本效益、准确性、人力资源要求和实验室设施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/9135468/eae09a34483d/11356_2022_21041_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/9135468/39ef0e821c03/11356_2022_21041_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/9135468/2b2ac338cc76/11356_2022_21041_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/9135468/40192bf4b2cb/11356_2022_21041_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/9135468/eae09a34483d/11356_2022_21041_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/9135468/39ef0e821c03/11356_2022_21041_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/9135468/4ff10b28b15d/11356_2022_21041_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/9135468/ca64f469821a/11356_2022_21041_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/9135468/2b2ac338cc76/11356_2022_21041_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/9135468/40192bf4b2cb/11356_2022_21041_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dcd/9135468/eae09a34483d/11356_2022_21041_Fig6_HTML.jpg

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