Waziri Bala, Alhaji Umar I, Oduwale Mubaraq A, Umar Halima Isah, Abdulmalik Aliyu M
Department of Medicine, Ibrahim Badamasi Babangida Specialist Hospital, Minna, Nigeria.
Ophthalmology Unit, General Hospital, Minna, Nigeria.
Oxf Med Case Reports. 2022 May 23;2022(5):omac026. doi: 10.1093/omcr/omac026. eCollection 2022 May.
Acute kidney injury (AKI) is generally associated with increased morbidity and mortality and is even more devastating in patients with comorbidities. Although AKI due to multiple bee stings is well established in the literature, it is still a rare entity with complex pathophysiologic mechanisms. The most commonly reported histological findings in AKI due to bee stings is acute tubular necrosis (ATN), with a few studies attributing it to acute interstitial nephritis (AIN), whereas the concurrence of both ATN and AIN is rarely reported. We hereby present a 50-year-old known Type 2 diabetes mellitus patient with a prior normal renal function, who developed AKI following multiple stings from >1000 bees. He had a kidney biopsy on account of non-recovery of his kidney function despite being on intermittent hemodialysis that showed combined features of ATN and AIN. He subsequently had a full recovery of his renal function following appropriate management.
急性肾损伤（AKI）通常与发病率和死亡率的增加相关，在合并症患者中甚至更具破坏性。尽管文献中已充分证实多次蜜蜂蜇伤可导致AKI，但它仍然是一种罕见的疾病，其病理生理机制复杂。蜜蜂蜇伤所致AKI最常报道的组织学表现是急性肾小管坏死（ATN），少数研究将其归因于急性间质性肾炎（AIN），而ATN和AIN同时存在的情况很少报道。我们在此报告一名50岁的2型糖尿病患者，其肾功能此前正常，在被1000多只蜜蜂多次蜇伤后发生了AKI。尽管他接受了间歇性血液透析，但肾功能仍未恢复，因此进行了肾活检，结果显示具有ATN和AIN的联合特征。经过适当治疗，他的肾功能随后完全恢复。
