Ditmars Frederick S, Lind Richard A, Broderick T Christopher, Fagg W Samuel
Department of Surgery, Transplant Division, The University of Texas Medical Branch, Galveston, TX, USA.
Carmel Foot Specialists, Charlotte, NC, USA.
SAGE Open Med Case Rep. 2022 May 21;10:2050313X221100882. doi: 10.1177/2050313X221100882. eCollection 2022.
Chronic, non-healing venous ulcers of the lower extremity are often limb-threatening conditions. Their management is characterized by a prolonged and frequently frustrating clinical course that represents an economic burden to both the patient and healthcare system. During the last two decades, thermal ablation of underlying incompetent venous systems has been extensively utilized to treat chronic venous insufficiency. Despite successful correction of venous hypertension, a substantial subgroup of patients remain affected by non-healing venous ulcers, thus posing a significant clinical challenge. In this case report, we detail quantitative and qualitative wound treatment course in a patient refractory to standard interventions, by treatment with a combination of cell-free amniotic fluid and dehydrated amniotic membrane following successful thermal ablation of refluxing veins.
下肢慢性、不愈合静脉溃疡通常是威胁肢体的病症。其治疗的特点是临床病程漫长且常常令人沮丧，这对患者和医疗系统来说都是经济负担。在过去二十年中，对潜在功能不全的静脉系统进行热消融已被广泛用于治疗慢性静脉功能不全。尽管成功纠正了静脉高压，但仍有相当一部分患者受到不愈合静脉溃疡的影响，因此构成了重大的临床挑战。在本病例报告中，我们详细介绍了一名对标准干预措施无效的患者的定量和定性伤口治疗过程，该患者在成功对反流静脉进行热消融后，采用无细胞羊水和脱水羊膜联合治疗。
