Hasani Hamidreza, Hakak-Zargar Benyamin, Mohammad Poor Nami Sahar, Mohammadian Khonsari Nami
Department of Ophthalmology, Madani Hospital, Alborz University of Medical Sciences, Karaj, Iran.
Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.
J Curr Ophthalmol. 2022 Apr 16;34(1):121-123. doi: 10.4103/joco.joco_277_21. eCollection 2022 Jan-Mar.
To report a case of bilateral central retinal vein occlusion (CRVO) associated with coronavirus-19 (COVID-19) infection.
A 43-year-old man presented to the emergency department with flu-like symptoms, severe erythema, a rash on his face, and respiratory distress. He was admitted to the intensive care unit, and the reverse transcriptase-polymerase chain reaction test was positive for the severe acute respiratory syndrome coronavirus-2 virus. The routine blood work was unremarkable. The dermatologist noted positive Nikolsky's sign, and the patient was diagnosed with Stevens-Johnson syndrome (SJS), which affected 18% of his body and was later confirmed by skin biopsy. Later, he reported worsening vision.
Ophthalmic examination and fundus fluorescein angiography showed bilateral CRVO. Despite best medical efforts, including treatment with systemic dexamethasone and remdesivir, the patient died on the 6 days of his hospitalization.
This was a rare bilateral CRVO and SJS case in a young patient, probably caused by the COVID-19 infection.
报告一例与冠状病毒病-19（COVID-19）感染相关的双侧视网膜中央静脉阻塞（CRVO）病例。
一名43岁男性因流感样症状、严重红斑、面部皮疹和呼吸窘迫就诊于急诊科。他被收入重症监护病房，严重急性呼吸综合征冠状病毒2病毒的逆转录聚合酶链反应检测呈阳性。常规血液检查无异常。皮肤科医生注意到尼氏征阳性，患者被诊断为史蒂文斯-约翰逊综合征（SJS），累及身体18%的面积，后来经皮肤活检确诊。后来，他报告视力恶化。
眼科检查和眼底荧光血管造影显示双侧CRVO。尽管尽了最大的医疗努力，包括全身使用地塞米松和瑞德西韦治疗，患者在住院第6天死亡。
这是一例年轻患者罕见的双侧CRVO和SJS病例，可能由COVID-19感染引起。
