Chen Rui, Liu Jichang, Zhang Yurou, Cai Weidong, Zhang Xinjiang, Xu Yanan, Dou Xingtang, Wang Zhanhong, Han Di, Wang Jiaming, Lin Guangyu, Wang Lingling, Sun Yinggang, Bai Zhixian, Gu Ming, Wang Zeying
College of Animal Science & Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.
Liaoning Province Modern Agricultural Production Base Construction Engineering Center, Shenyang, China.
Anim Biotechnol. 2023 Dec;34(7):2094-2105. doi: 10.1080/10495398.2022.2077212. Epub 2022 May 27.
Reproductive traits have a high economic value in goat breeding, and increasing the number of lambs produced by ewes is of great importance to improve the production efficiency of goat farming. Lambing traits in goats are low heritability traits, but their genetic basis is ultimately determined by genes. This study aimed to investigate the relationship between , , and gene polymorphisms and production performance, such as lambing, cashmere production, milk production, and body size in Liaoning cashmere goats. A total of six single nucleotide polymorphisms (SNPs) loci were identified in these three genes, G144A and T504C on the gene, A56G, G144A, G490C on the gene, and G109519T on the gene. For lambing and cashmere production traits, the AA genotype of G144A on the gene, TT on the T504C genotype, GG genotype of G144A on the gene, A56G, G144A, and T504C on and G109519T on gene are dominant genotypes. AATT is a dominant haplotype combination. Allele G can be used as a molecular marker for lambing, cashmere, and milk production traits in Liaoning cashmere goats. Marker-assisted selection can be used for early selection to achieve improvement of genetic traits in Liaoning cashmere goats.
繁殖性状在山羊育种中具有很高的经济价值，提高母羊产羔数对提高山羊养殖生产效率至关重要。山羊的产羔性状是低遗传力性状，但其遗传基础最终由基因决定。本研究旨在探讨辽宁绒山羊中、和基因多态性与产羔、产绒、产奶和体尺等生产性能之间的关系。在这三个基因中总共鉴定出6个单核苷酸多态性（SNP）位点，基因上的G144A和T504C，基因上的A56G、G144A、G490C，以及基因上的G109519T。对于产羔和产绒性状，基因上G144A的AA基因型、T504C基因型的TT、基因上G144A的GG基因型、基因上的A56G、G144A和T504C以及基因上的G109519T是优势基因型。AATT是优势单倍型组合。等位基因G可用作辽宁绒山羊产羔、产绒和产奶性状的分子标记。标记辅助选择可用于早期选择，以实现辽宁绒山羊遗传性状的改良。
