Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou, China.
Phytother Res. 2022 Aug;36(8):3080-3101. doi: 10.1002/ptr.7500. Epub 2022 May 27.
This umbrella review is to recapitulate and grade the available evidence of associations between consumption of Zingiberaceae plants/curcumin (Cur) and multiple health-related outcomes. This study included 161 meta-analyses of randomized controlled trials in 76 articles with 67 unique health outcomes. Data on heterogeneity and publication bias are considered to assess the quality of evidence. Based on the different impact of Zingiberaceae plants/Cur on human health, the advantages outweigh the disadvantages. Zingiberaceae plants/Cur can mainly improve metabolic syndrome, non-alcoholic fatty liver disease, cardiovascular disease, and some chronic inflammatory diseases, likewise, obviously relief the pain of osteoarthritis and related diseases. Ginger supplements have been shown to improve vomiting during pregnancy and to relieve nausea and vomiting caused by chemotherapy and surgery. The surgery is any type of surgery, including laparoscopic surgery, gynecological surgery and mixed surgery. Beneficial associations were found with Cur intervention in gastrointestinal, neurological and oral diseases. Zingiberaceae plants/Cur are generally safe and favorable for multiple health outcomes in humans. High-quality research is further needed to prove the observed associations.
这篇伞式综述旨在总结和评估姜科植物/姜黄素（Cur）的消费与多种健康相关结局之间的关联证据。本研究纳入了 76 篇文章中的 161 项随机对照试验的荟萃分析，涉及 67 种独特的健康结局。考虑了异质性和发表偏倚的数据，以评估证据质量。基于姜科植物/姜黄素对人类健康的不同影响，其利大于弊。姜科植物/姜黄素主要可以改善代谢综合征、非酒精性脂肪肝、心血管疾病和一些慢性炎症性疾病，同样明显缓解骨关节炎及相关疾病的疼痛。姜补充剂已被证明可改善妊娠呕吐，并缓解化疗和手术引起的恶心和呕吐。手术是任何类型的手术，包括腹腔镜手术、妇科手术和混合手术。Cur 干预与胃肠道、神经和口腔疾病之间存在有益关联。姜科植物/姜黄素通常对人类的多种健康结局是安全和有利的。需要进一步进行高质量的研究来证明观察到的关联。
