EuroQol Group, Rotterdam, The Netherlands.
Department of Health Economics and Health Care Management, Bielefeld University, 33615, Bielefeld, Germany.
Qual Life Res. 2022 Nov;31(11):3267-3282. doi: 10.1007/s11136-022-03158-3. Epub 2022 May 27.
To determine feasibility and validity of the EQ-5D-3L in the elderly European population.
Secondary data analysis based on the study of health, ageing, and retirement in Europe (SHARE) to determine the percentage of missing items for EQ-5D dimensions and EQ VAS, and to demonstrate convergent/divergent validity with measures included in the SHARE survey. Known-groups validity was tested using literature-based hypotheses. Correlation coefficients and Cohen's f are reported.
Missing values were below 3% across all EQ-5D dimensions and gender strata, slightly increasing with age. Individuals' responses to each EQ-5D dimension were related to their ratings of other measures in expected directions. The EQ VAS and all EQ-5D dimensions (except anxiety/depression) moderately to strongly correlated with physical [e.g. number of limitations in activities of daily living (ADL): r = 0.313-0.658] and generic measures [CASP (control, autonomy, self-realization, pleasure)-19 scale, self-perceived health, number of symptoms: r = 0.318-0.622], while anxiety/depression strongly correlated with the EURO-D scale (r = 0.527). Both EQ-5D dimensions and EQ VAS discriminated well between two [or more] groups known to differ [e.g. anxiety/depression discriminated well between persons classified as depressed/not depressed using the EURO-D scale, f = 0.51; self-care differentiated best between individuals without and with 1 + ADL limitations, f = 0.69]. Sociodemographic variables like gender, education, and partner in household were hardly associated with EQ VAS scores (f < 0.25).
With item non-response of less than 3%, good discriminatory, and construct properties, the EQ-5D-3L showed to be a feasible and valid measure in the elderly Europeans.
确定 EQ-5D-3L 在欧洲老年人中的可行性和有效性。
基于健康、老龄化和退休研究（SHARE）的二次数据分析，确定 EQ-5D 维度和 EQ VAS 的缺失项目百分比，并展示与 SHARE 调查中包含的措施的收敛/发散有效性。使用基于文献的假设测试了已知组的有效性。报告相关系数和 Cohen's f。
所有 EQ-5D 维度和性别分层的缺失值均低于 3%，略随年龄增加而增加。个体对每个 EQ-5D 维度的反应与其对其他措施的评分呈预期方向相关。EQ VAS 和所有 EQ-5D 维度（焦虑/抑郁除外）与身体相关[例如日常生活活动（ADL）的限制数量：r=0.313-0.658]和通用措施[CASP（控制、自主、自我实现、愉悦）-19 量表、自我感知健康、症状数量：r=0.318-0.622]中度至高度相关，而焦虑/抑郁与 EURO-D 量表强烈相关（r=0.527）。EQ-5D 维度和 EQ VAS 很好地区分了已知差异的两个[或更多]组[例如，使用 EURO-D 量表，焦虑/抑郁很好地区分了抑郁/不抑郁的人群，f=0.51；自我护理在无 ADL 限制和 1+ADL 限制的个体之间区分最佳，f=0.69]。性别、教育和家庭伴侣等社会人口变量与 EQ VAS 评分几乎没有关联（f<0.25）。
EQ-5D-3L 具有小于 3%的项目无应答率、良好的区分度和结构特性，表明在欧洲老年人中是一种可行和有效的测量工具。
