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《欧洲老年人中 EQ-5D-3L 的可行性和有效性:利用 SHARE(d) 数据进行的二次数据分析》

Feasibility and validity of the EQ-5D-3L in the elderly Europeans: a secondary data analysis using SHARE(d) data.

机构信息

EuroQol Group, Rotterdam, The Netherlands.

Department of Health Economics and Health Care Management, Bielefeld University, 33615, Bielefeld, Germany.

出版信息

Qual Life Res. 2022 Nov;31(11):3267-3282. doi: 10.1007/s11136-022-03158-3. Epub 2022 May 27.

Abstract

PURPOSE

To determine feasibility and validity of the EQ-5D-3L in the elderly European population.

METHODS

Secondary data analysis based on the study of health, ageing, and retirement in Europe (SHARE) to determine the percentage of missing items for EQ-5D dimensions and EQ VAS, and to demonstrate convergent/divergent validity with measures included in the SHARE survey. Known-groups validity was tested using literature-based hypotheses. Correlation coefficients and Cohen's f are reported.

RESULTS

Missing values were below 3% across all EQ-5D dimensions and gender strata, slightly increasing with age. Individuals' responses to each EQ-5D dimension were related to their ratings of other measures in expected directions. The EQ VAS and all EQ-5D dimensions (except anxiety/depression) moderately to strongly correlated with physical [e.g. number of limitations in activities of daily living (ADL): r = 0.313-0.658] and generic measures [CASP (control, autonomy, self-realization, pleasure)-19 scale, self-perceived health, number of symptoms: r = 0.318-0.622], while anxiety/depression strongly correlated with the EURO-D scale (r = 0.527). Both EQ-5D dimensions and EQ VAS discriminated well between two [or more] groups known to differ [e.g. anxiety/depression discriminated well between persons classified as depressed/not depressed using the EURO-D scale, f = 0.51; self-care differentiated best between individuals without and with 1 + ADL limitations, f = 0.69]. Sociodemographic variables like gender, education, and partner in household were hardly associated with EQ VAS scores (f < 0.25).

CONCLUSION

With item non-response of less than 3%, good discriminatory, and construct properties, the EQ-5D-3L showed to be a feasible and valid measure in the elderly Europeans.

摘要

目的

确定 EQ-5D-3L 在欧洲老年人中的可行性和有效性。

方法

基于健康、老龄化和退休研究(SHARE)的二次数据分析,确定 EQ-5D 维度和 EQ VAS 的缺失项目百分比,并展示与 SHARE 调查中包含的措施的收敛/发散有效性。使用基于文献的假设测试了已知组的有效性。报告相关系数和 Cohen's f。

结果

所有 EQ-5D 维度和性别分层的缺失值均低于 3%,略随年龄增加而增加。个体对每个 EQ-5D 维度的反应与其对其他措施的评分呈预期方向相关。EQ VAS 和所有 EQ-5D 维度(焦虑/抑郁除外)与身体相关[例如日常生活活动(ADL)的限制数量:r=0.313-0.658]和通用措施[CASP(控制、自主、自我实现、愉悦)-19 量表、自我感知健康、症状数量:r=0.318-0.622]中度至高度相关,而焦虑/抑郁与 EURO-D 量表强烈相关(r=0.527)。EQ-5D 维度和 EQ VAS 很好地区分了已知差异的两个[或更多]组[例如,使用 EURO-D 量表,焦虑/抑郁很好地区分了抑郁/不抑郁的人群,f=0.51;自我护理在无 ADL 限制和 1+ADL 限制的个体之间区分最佳,f=0.69]。性别、教育和家庭伴侣等社会人口变量与 EQ VAS 评分几乎没有关联(f<0.25)。

结论

EQ-5D-3L 具有小于 3%的项目无应答率、良好的区分度和结构特性,表明在欧洲老年人中是一种可行和有效的测量工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d93/9546963/4f623f07935a/11136_2022_3158_Fig1_HTML.jpg

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