Di Spirito Federica, Scelza Giuseppe, Fornara Roberto, Giordano Francesco, Rosa Donato, Amato Alessandra
Department of Medicine, Surgery and Dentistry "Schola Medica Salernitana", University of Salerno, Baronissi, 84081 Salerno, Italy.
Private Practitioner, 20010 Milan, Italy.
Healthcare (Basel). 2022 Apr 19;10(5):760. doi: 10.3390/healthcare10050760.
Endodontic treatment comprises the overall management of pre-, intra- and post-operative symptoms, including post-operative endodontic pain, considered as a complication susceptible of chronicization. Post-operative pain is very common and highly unpreventable and has a multi-factorial etiology and a potential pathogenic link to the acute inflammation of the periapical area, secondary to localized chemical, mechanical, host and/or microbial damage occurring during endodontic treatment. Considering the multitude of heterogeneous technical and pharmacological approaches proposed to control post-operative endodontic pain, the present study primarily comprised an overview of systematic reviews of systematic reviews of randomized clinical trials, summarizing findings on post-operatively administered oral medications for post-operative endodontic pain control, in order to note the most effective type and dosage of such drugs. Secondarily, a narrative review of the current evidence on technical solutions to be observed during endodontic treatment procedures, to control post-operative pain, was conducted to provide integrated evidence-based clinical recommendations for optimal post-operative endodontic pain management.
牙髓治疗包括术前、术中和术后症状的全面管理，其中术后牙髓疼痛被视为一种易慢性化的并发症。术后疼痛非常常见且极难预防，其病因是多因素的，并且与根管治疗期间发生的局部化学、机械、宿主和/或微生物损伤继发的根尖周区域急性炎症存在潜在的致病联系。考虑到为控制术后牙髓疼痛而提出的众多不同技术和药理学方法，本研究主要包括对随机临床试验的系统评价的系统评价进行概述，总结关于术后口服药物用于控制术后牙髓疼痛的研究结果，以便指出此类药物最有效的类型和剂量。其次，对根管治疗过程中为控制术后疼痛而应采用的技术解决方案的现有证据进行叙述性综述，以提供基于循证的综合临床建议，实现最佳的术后牙髓疼痛管理。
