Schiefer Jennifer Lynn, Andreae Janine, Fuchs Paul Christian, Lefering Rolf, Heidekrueger Paul Immanuel, Schulz Alexandra, Bagheri Mahsa
Clinic of Plastic, Reconstructive, Hand and Burn Surgery, Hospital Cologne Merheim, University of Witten-Herdecke, 58448 Witten, Germany.
Institute for Research in Operative Medicine (IFOM), University of Witten-Herdecke, 50933 Cologne, Germany.
J Clin Med. 2022 May 18;11(10):2857. doi: 10.3390/jcm11102857.
Various synthetic and biological wound dressings are available for the treatment of superficial burns, and standard care differs among hospitals. Nevertheless, the search for an ideal wound dressing offering a safe healing environment as well as optimal scar quality while being economically attractive is a continuing process. In recent years, Dressilk, which consists of pure silk, has become the standard of care for the treatment of superficial burns in our hospital. However, no long-term scar-evaluation studies have been performed to compare Dressilk with the often-used and more expensive Suprathel in the treatment of superficial burns.
Subjective and objective scar evaluations were performed three, six, and twelve months after treatment in patients who received simultaneous treatment of 20 superficial burn wounds with both Suprathel and Dressilk. The evaluations were performed using the Vancouver Scar Scale, the Cutometer, Mexameter, Tewameter, and the O2C.
Both dressings showed mostly equivalent results in subjective scar evaluations. In the objective scar evaluations, the wounds treated with Dressilk showed a faster return to the qualities of non-injured skin. Wound areas treated with the two dressings showed no significant differences in elasticity and transepidermal water loss after 12 months. Only oxygen saturation was significantly lower in wound areas treated with Suprathel ( = 0.008). Subjectively, wound areas treated with Dressilk showed significantly higher pigmentation after six months, which was not apparent after 12 months.
Both wound dressings led to esthetically satisfying scar recovery without significant differences from normal uninjured skin after 12 months. Therefore, Dressilk remains an economically and clinically interesting alternative to Suprathel for the treatment of superficial burns.
有多种合成和生物伤口敷料可用于治疗浅度烧伤,不同医院的标准护理也有所不同。然而,寻找一种理想的伤口敷料,既能提供安全的愈合环境,又能保证最佳的瘢痕质量,同时还具有经济吸引力,这是一个持续的过程。近年来,由纯丝绸制成的Dressilk已成为我院治疗浅度烧伤的护理标准。然而,尚未进行长期瘢痕评估研究,以比较Dressilk与常用且更昂贵的Suprathel在治疗浅度烧伤方面的效果。
对同时使用Suprathel和Dressilk治疗20个浅度烧伤伤口的患者,在治疗后3个月、6个月和12个月进行主观和客观瘢痕评估。评估使用温哥华瘢痕量表、皮肤弹性测量仪、皮肤颜色测量仪、经皮水分流失测量仪和O2C进行。
在主观瘢痕评估中,两种敷料的结果大多相当。在客观瘢痕评估中,用Dressilk治疗的伤口恢复到未受伤皮肤质量的速度更快。两种敷料治疗的伤口区域在12个月后弹性和经皮水分流失无显著差异。仅用Suprathel治疗的伤口区域氧饱和度显著较低(P = 0.008)。主观上,用Dressilk治疗的伤口区域在6个月后色素沉着明显较高,12个月后不明显。
两种伤口敷料均使瘢痕恢复美观,12个月后与正常未受伤皮肤无显著差异。因此,在治疗浅度烧伤方面,Dressilk仍是Suprathel在经济和临床方面颇具吸引力的替代产品。